68682

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 327962..328494 Replicon chromosome
Accession NZ_CP018095
Organism Chelatococcus daeguensis strain TAD1

Toxin (Protein)


Gene name mazF Uniprot ID A0A0K6HDL4
Locus tag BOQ54_RS01510 Protein ID WP_055459613.1
Coordinates 327962..328285 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID A0A0K6HDD1
Locus tag BOQ54_RS01515 Protein ID WP_055459614.1
Coordinates 328282..328494 (-) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BOQ54_RS01485 323714..324499 + 786 WP_071924356.1 3-hydroxybutyrate dehydrogenase -
BOQ54_RS01490 324496..325587 + 1092 WP_082464821.1 patatin-like phospholipase family protein -
BOQ54_RS01495 325609..326154 + 546 WP_055459610.1 O-acetyl-ADP-ribose deacetylase -
BOQ54_RS01500 326157..326816 - 660 WP_055459611.1 methyltransferase -
BOQ54_RS01505 326813..327955 - 1143 WP_071923112.1 glycosyltransferase -
BOQ54_RS01510 327962..328285 - 324 WP_055459613.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
BOQ54_RS01515 328282..328494 - 213 WP_055459614.1 antitoxin MazE family protein Antitoxin
BOQ54_RS01520 328565..330091 - 1527 WP_071923113.1 altronate dehydratase family protein -
BOQ54_RS01525 330194..330643 - 450 WP_071923114.1 fucose-binding protein -
BOQ54_RS01530 330667..331701 - 1035 WP_063186580.1 aldo/keto reductase -
BOQ54_RS01535 331713..333008 - 1296 WP_055459618.1 TRAP transporter large permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-105)

Antitoxin

Antitoxin MazE-like

(6-68)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11649.62 Da        Isoelectric Point: 10.5864

>T68682 WP_055459613.1 NZ_CP018095:c328285-327962 [Chelatococcus daeguensis]
MRRGDLVTVALPGAYGKLRPALIIQSDLFSTHPSFTLLPVTSELVAAPLLRITVEPNERNGLQKVSQIMVDKAHTVPRGR
LGQSFGRLDETDLLAVNRALALFLGFA

Download         Length: 324 bp

>T68682 NZ_CP018095:c328285-327962 [Chelatococcus daeguensis]
ATGAGGCGCGGTGACCTCGTCACCGTGGCTCTTCCCGGGGCCTATGGCAAACTAAGACCGGCCCTGATCATCCAGTCGGA
TCTCTTCAGCACGCATCCCTCCTTCACCTTGCTGCCGGTGACGAGTGAACTCGTCGCGGCGCCGCTCCTGCGCATCACGG
TCGAGCCGAATGAGCGCAACGGCCTGCAGAAGGTCTCGCAGATCATGGTGGACAAGGCTCACACGGTGCCCCGCGGCAGG
CTGGGCCAGTCTTTCGGCCGGCTCGACGAGACGGATCTTCTCGCGGTAAACCGCGCGCTCGCGCTCTTTCTCGGTTTTGC
GTGA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8022.08 Da        Isoelectric Point: 7.1679

>AT68682 WP_055459614.1 NZ_CP018095:c328494-328282 [Chelatococcus daeguensis]
MAGVAKRVQRHRERLRAAGLKPVQIWIPDPAQPGFAEECRRQSQLIAKSAEEDEILDFIEAASDHRGWRE

Download         Length: 213 bp

>AT68682 NZ_CP018095:c328494-328282 [Chelatococcus daeguensis]
ATGGCAGGGGTCGCCAAGCGTGTGCAGCGCCATCGCGAGCGGTTACGGGCGGCCGGGTTGAAGCCTGTGCAGATCTGGAT
ACCGGACCCGGCGCAGCCCGGCTTTGCCGAGGAGTGTCGACGCCAGTCACAACTCATCGCCAAGAGCGCCGAGGAAGACG
AGATCCTCGATTTCATCGAAGCGGCCTCGGATCATCGGGGCTGGCGTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K6HDL4

Antitoxin

Source ID Structure
AlphaFold DB A0A0K6HDD1

References