Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 115756..116390 Replicon chromosome
Accession NZ_CP018091
Organism Synechococcus sp. SynAce01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BM449_RS00620 Protein ID WP_186437673.1
Coordinates 115756..116058 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A1J0P730
Locus tag BM449_RS00625 Protein ID WP_071799670.1
Coordinates 116058..116390 (+) Length 111 a.a.

Genomic Context


BM449_RS00605BM449_RS00610BM449_RS15130BM449_RS00620BM449_RS00625BM449_RS00630BM449_RS00645BM449_RS00635BM449_RS00640
Location: 111120..111737 (618 bp)
Type: Others
Protein ID: WP_071799666.1
Location: 111734..115219 (3486 bp)
Type: Others
Protein ID: WP_071799667.1
Location: 115570..115737 (168 bp)
Type: Others
Protein ID: WP_186437671.1
Location: 115756..116058 (303 bp)
Type: Toxin
Protein ID: WP_186437673.1
Location: 116058..116390 (333 bp)
Type: Antitoxin
Protein ID: WP_071799670.1
Location: 116441..118246 (1806 bp)
Type: Others
Protein ID: WP_162922806.1
Location: 119988..120293 (306 bp)
Type: Others
Protein ID: WP_071801801.1
Location: 118210..119148 (939 bp)
Type: Others
Protein ID: WP_071799672.1
Location: 119327..119515 (189 bp)
Type: Others
Protein ID: WP_071799673.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BM449_RS00605111120..111737+618WP_071799666.1DUF1788 domain-containing protein-
BM449_RS00610111734..115219+3486WP_071799667.1BREX system P-loop protein BrxC-
BM449_RS15130115570..115737+168WP_186437671.1hypothetical protein-
BM449_RS00620115756..116058+303WP_186437673.1type II toxin-antitoxin system RelE/ParE family toxinToxin
BM449_RS00625116058..116390+333WP_071799670.1putative addiction module antidote proteinAntitoxin
BM449_RS00630116441..118246+1806WP_162922806.1BREX-1 system adenine-specific DNA-methyltransferase PglX-
BM449_RS00635118210..119148-939WP_071799672.1IS481 family transposase-
BM449_RS00640119327..119515-189WP_071799673.1hypothetical protein-
BM449_RS00645119988..120293+306WP_071801801.1MTH1187 family thiamine-binding protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11283.87 Da        Isoelectric Point: 9.3924

>T68675 WP_186437673.1 NZ_CP018091:115756-116058 [Synechococcus sp. SynAce01]
MMRVVKSEVYQAWIDGLRDQAGRARVLMRVDRLIHGNPGDYRNLTEGVSELKIDVGPGYRVYYARRGDHLLLLLGGGSKA
TQAKDIAKALDLNREFEDHS

Download         Length: 303 bp

>T68675 NZ_CP018091:115756-116058 [Synechococcus sp. SynAce01]
CTGATGAGGGTCGTCAAGTCGGAGGTCTACCAAGCGTGGATCGACGGCCTCAGGGATCAAGCCGGCAGGGCTCGAGTGTT
GATGCGAGTGGATCGCTTGATCCATGGCAACCCCGGCGACTATCGCAATCTCACGGAGGGAGTGTCTGAACTGAAAATCG
ATGTCGGACCCGGCTACCGGGTGTATTACGCCCGAAGAGGCGATCACCTGCTTCTGCTGTTGGGCGGGGGCAGTAAAGCG
ACCCAGGCCAAAGACATCGCCAAGGCTCTTGATTTAAACCGTGAATTTGAGGATCACTCGTGA

Antitoxin


Download         Length: 111 a.a.        Molecular weight: 11721.24 Da        Isoelectric Point: 5.6007

>AT68675 WP_071799670.1 NZ_CP018091:116058-116390 [Synechococcus sp. SynAce01]
MNQAQPLANPSATRFTPYDVAEHLRTPDEMAAYLDAWLEEAPDDVAGLARALGDIARAKGMTQVAKDTGLSRESLYRALS
ADGNPSFATVLKVTKALGLRLHAHAVACEG

Download         Length: 333 bp

>AT68675 NZ_CP018091:116058-116390 [Synechococcus sp. SynAce01]
ATGAACCAAGCCCAACCCCTTGCTAATCCATCGGCAACCAGGTTCACGCCCTATGACGTGGCCGAGCATCTCAGAACGCC
AGATGAGATGGCGGCCTATCTGGATGCCTGGCTTGAGGAAGCACCGGATGATGTGGCCGGTCTTGCACGGGCCTTGGGGG
ACATTGCCCGAGCCAAGGGGATGACACAGGTGGCGAAAGACACGGGCCTCAGCCGGGAGAGCCTTTATCGGGCGCTCAGC
GCCGATGGCAATCCAAGCTTCGCCACCGTGCTGAAGGTGACCAAGGCTCTGGGCTTGCGGCTTCATGCCCATGCCGTTGC
TTGTGAGGGTTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1J0P730

References