Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-PumB/upstrm_HI1419-dnstrm_HI1420 |
Location | 115756..116390 | Replicon | chromosome |
Accession | NZ_CP018091 | ||
Organism | Synechococcus sp. SynAce01 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | BM449_RS00620 | Protein ID | WP_186437673.1 |
Coordinates | 115756..116058 (+) | Length | 101 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | A0A1J0P730 |
Locus tag | BM449_RS00625 | Protein ID | WP_071799670.1 |
Coordinates | 116058..116390 (+) | Length | 111 a.a. |
Genomic Context
Location: 111120..111737 (618 bp)
Type: Others
Protein ID: WP_071799666.1
Type: Others
Protein ID: WP_071799666.1
Location: 111734..115219 (3486 bp)
Type: Others
Protein ID: WP_071799667.1
Type: Others
Protein ID: WP_071799667.1
Location: 115570..115737 (168 bp)
Type: Others
Protein ID: WP_186437671.1
Type: Others
Protein ID: WP_186437671.1
Location: 115756..116058 (303 bp)
Type: Toxin
Protein ID: WP_186437673.1
Type: Toxin
Protein ID: WP_186437673.1
Location: 116058..116390 (333 bp)
Type: Antitoxin
Protein ID: WP_071799670.1
Type: Antitoxin
Protein ID: WP_071799670.1
Location: 116441..118246 (1806 bp)
Type: Others
Protein ID: WP_162922806.1
Type: Others
Protein ID: WP_162922806.1
Location: 119988..120293 (306 bp)
Type: Others
Protein ID: WP_071801801.1
Type: Others
Protein ID: WP_071801801.1
Location: 118210..119148 (939 bp)
Type: Others
Protein ID: WP_071799672.1
Type: Others
Protein ID: WP_071799672.1
Location: 119327..119515 (189 bp)
Type: Others
Protein ID: WP_071799673.1
Type: Others
Protein ID: WP_071799673.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BM449_RS00605 | 111120..111737 | + | 618 | WP_071799666.1 | DUF1788 domain-containing protein | - |
BM449_RS00610 | 111734..115219 | + | 3486 | WP_071799667.1 | BREX system P-loop protein BrxC | - |
BM449_RS15130 | 115570..115737 | + | 168 | WP_186437671.1 | hypothetical protein | - |
BM449_RS00620 | 115756..116058 | + | 303 | WP_186437673.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
BM449_RS00625 | 116058..116390 | + | 333 | WP_071799670.1 | putative addiction module antidote protein | Antitoxin |
BM449_RS00630 | 116441..118246 | + | 1806 | WP_162922806.1 | BREX-1 system adenine-specific DNA-methyltransferase PglX | - |
BM449_RS00635 | 118210..119148 | - | 939 | WP_071799672.1 | IS481 family transposase | - |
BM449_RS00640 | 119327..119515 | - | 189 | WP_071799673.1 | hypothetical protein | - |
BM449_RS00645 | 119988..120293 | + | 306 | WP_071801801.1 | MTH1187 family thiamine-binding protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11283.87 Da Isoelectric Point: 9.3924
>T68675 WP_186437673.1 NZ_CP018091:115756-116058 [Synechococcus sp. SynAce01]
MMRVVKSEVYQAWIDGLRDQAGRARVLMRVDRLIHGNPGDYRNLTEGVSELKIDVGPGYRVYYARRGDHLLLLLGGGSKA
TQAKDIAKALDLNREFEDHS
MMRVVKSEVYQAWIDGLRDQAGRARVLMRVDRLIHGNPGDYRNLTEGVSELKIDVGPGYRVYYARRGDHLLLLLGGGSKA
TQAKDIAKALDLNREFEDHS
Download Length: 303 bp
>T68675 NZ_CP018091:115756-116058 [Synechococcus sp. SynAce01]
CTGATGAGGGTCGTCAAGTCGGAGGTCTACCAAGCGTGGATCGACGGCCTCAGGGATCAAGCCGGCAGGGCTCGAGTGTT
GATGCGAGTGGATCGCTTGATCCATGGCAACCCCGGCGACTATCGCAATCTCACGGAGGGAGTGTCTGAACTGAAAATCG
ATGTCGGACCCGGCTACCGGGTGTATTACGCCCGAAGAGGCGATCACCTGCTTCTGCTGTTGGGCGGGGGCAGTAAAGCG
ACCCAGGCCAAAGACATCGCCAAGGCTCTTGATTTAAACCGTGAATTTGAGGATCACTCGTGA
CTGATGAGGGTCGTCAAGTCGGAGGTCTACCAAGCGTGGATCGACGGCCTCAGGGATCAAGCCGGCAGGGCTCGAGTGTT
GATGCGAGTGGATCGCTTGATCCATGGCAACCCCGGCGACTATCGCAATCTCACGGAGGGAGTGTCTGAACTGAAAATCG
ATGTCGGACCCGGCTACCGGGTGTATTACGCCCGAAGAGGCGATCACCTGCTTCTGCTGTTGGGCGGGGGCAGTAAAGCG
ACCCAGGCCAAAGACATCGCCAAGGCTCTTGATTTAAACCGTGAATTTGAGGATCACTCGTGA
Antitoxin
Download Length: 111 a.a. Molecular weight: 11721.24 Da Isoelectric Point: 5.6007
>AT68675 WP_071799670.1 NZ_CP018091:116058-116390 [Synechococcus sp. SynAce01]
MNQAQPLANPSATRFTPYDVAEHLRTPDEMAAYLDAWLEEAPDDVAGLARALGDIARAKGMTQVAKDTGLSRESLYRALS
ADGNPSFATVLKVTKALGLRLHAHAVACEG
MNQAQPLANPSATRFTPYDVAEHLRTPDEMAAYLDAWLEEAPDDVAGLARALGDIARAKGMTQVAKDTGLSRESLYRALS
ADGNPSFATVLKVTKALGLRLHAHAVACEG
Download Length: 333 bp
>AT68675 NZ_CP018091:116058-116390 [Synechococcus sp. SynAce01]
ATGAACCAAGCCCAACCCCTTGCTAATCCATCGGCAACCAGGTTCACGCCCTATGACGTGGCCGAGCATCTCAGAACGCC
AGATGAGATGGCGGCCTATCTGGATGCCTGGCTTGAGGAAGCACCGGATGATGTGGCCGGTCTTGCACGGGCCTTGGGGG
ACATTGCCCGAGCCAAGGGGATGACACAGGTGGCGAAAGACACGGGCCTCAGCCGGGAGAGCCTTTATCGGGCGCTCAGC
GCCGATGGCAATCCAAGCTTCGCCACCGTGCTGAAGGTGACCAAGGCTCTGGGCTTGCGGCTTCATGCCCATGCCGTTGC
TTGTGAGGGTTGA
ATGAACCAAGCCCAACCCCTTGCTAATCCATCGGCAACCAGGTTCACGCCCTATGACGTGGCCGAGCATCTCAGAACGCC
AGATGAGATGGCGGCCTATCTGGATGCCTGGCTTGAGGAAGCACCGGATGATGTGGCCGGTCTTGCACGGGCCTTGGGGG
ACATTGCCCGAGCCAAGGGGATGACACAGGTGGCGAAAGACACGGGCCTCAGCCGGGAGAGCCTTTATCGGGCGCTCAGC
GCCGATGGCAATCCAAGCTTCGCCACCGTGCTGAAGGTGACCAAGGCTCTGGGCTTGCGGCTTCATGCCCATGCCGTTGC
TTGTGAGGGTTGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
No matching records found |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1J0P730 |