Detailed information of TA system TA068672

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2839612..2840168
• Replicon: chromosome
• Accession: NZ_CP018087
• Organism: Xanthomonas oryzae pv. oryzae strain ScYc-b

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BO992_RS14115
• Protein ID: WP_027703932.1
• Coordinates: 2839612..2839902 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: BO992_RS14120
• Protein ID: WP_011408759.1
• Coordinates: 2839890..2840168 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BO992_RS14065	2835382..2836473	+	1092	WP_041182166.1	ribonuclease D	-
BO992_RS14070	2836549..2836886	-	338	Protein_2535	ATP-dependent DNA ligase	-
BO992_RS24400	2836946..2837152	-	207	Protein_2536	hypothetical protein	-
BO992_RS14080	2837168..2837344	-	177	Protein_2537	DUF3606 domain-containing protein	-
BO992_RS14085	2837566..2837967	+	402	WP_011259345.1	H-NS histone family protein	-
BO992_RS14105	2838831..2839010	-	180	WP_015463309.1	hypothetical protein	-
BO992_RS24405	2839154..2839351	-	198	WP_004541336.1	hypothetical protein	-
BO992_RS14115	2839612..2839902	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BO992_RS14120	2839890..2840168	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
BO992_RS24625	2840249..2840452	-	204	WP_199285669.1	hypothetical protein	-
BO992_RS24630	2840364..2840708	-	345	WP_199285675.1	hypothetical protein	-
BO992_RS14130	2840653..2840853	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
BO992_RS14135	2841614..2842798	-	1185	WP_011408760.1	IS256 family transposase	-
BO992_RS14145	2843379..2844344	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
BO992_RS14150	2844446..2845051	+	606	Protein_2548	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T68672 WP_027703932.1 NZ_CP018087:c2839902-2839612 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T68672 NZ_CP018087:c2839902-2839612 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT68672 WP_011408759.1 NZ_CP018087:c2840168-2839890 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT68672 NZ_CP018087:c2840168-2839890 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2