Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 317863..318406 Replicon plasmid unnamed5
Accession NZ_CP018081
Organism Sulfitobacter sp. AM1-D1

Toxin (Protein)


Gene name parE Uniprot ID A0A1J0WPP0
Locus tag BOO69_RS22655 Protein ID WP_071974422.1
Coordinates 317863..318162 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A225NCU8
Locus tag BOO69_RS22660 Protein ID WP_037207773.1
Coordinates 318155..318406 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BOO69_RS22650 313340..317737 - 4398 WP_071974421.1 strawberry notch family protein -
BOO69_RS22655 317863..318162 - 300 WP_071974422.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BOO69_RS22660 318155..318406 - 252 WP_037207773.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
BOO69_RS22665 318457..319101 - 645 WP_071974423.1 hypothetical protein -
BOO69_RS22670 319208..319684 - 477 WP_071974424.1 hypothetical protein -
BOO69_RS22675 319686..320069 - 384 WP_071974425.1 hypothetical protein -
BOO69_RS22680 320149..320445 - 297 WP_071974426.1 hypothetical protein -
BOO69_RS22685 320563..320943 - 381 WP_071974427.1 DUF3768 domain-containing protein -
BOO69_RS22690 321070..323241 - 2172 WP_071974428.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..348874 348874


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-91)

Antitoxin

Antitoxin ParD

(3-74)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11519.17 Da        Isoelectric Point: 7.4752

>T68668 WP_071974422.1 NZ_CP018081:c318162-317863 [Sulfitobacter sp. AM1-D1]
MRKIHHSQAAKSDLVDIWVETHRQWGEAQADRYLDDIERALKGLIANPQMGSDCSDLLQGARKLITGRHLVFYEVDPDRI
FVIRVLHQSMDVPRHLRSF

Download         Length: 300 bp

>T68668 NZ_CP018081:c318162-317863 [Sulfitobacter sp. AM1-D1]
ATGCGTAAAATCCATCACTCACAGGCGGCAAAATCCGATCTCGTCGATATCTGGGTCGAGACACATCGACAATGGGGCGA
GGCGCAGGCGGACCGCTATCTCGACGATATCGAGCGTGCTCTGAAGGGACTGATCGCCAATCCTCAAATGGGGTCTGACT
GTTCCGATCTCTTGCAGGGCGCGCGGAAACTGATCACGGGTCGGCATCTTGTGTTCTATGAGGTGGACCCGGACAGGATA
TTCGTGATCCGGGTTTTGCATCAATCCATGGACGTGCCGCGGCATCTGCGGTCGTTCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9153.32 Da        Isoelectric Point: 5.1425

>AT68668 WP_037207773.1 NZ_CP018081:c318406-318155 [Sulfitobacter sp. AM1-D1]
MASTSVTLGPHWDEFIALMLKEGRYGSTSELIRASLRLMEEQEGQRARLRVALMEGKQSGDAGPLDMDEIKREARSRSGA
SDA

Download         Length: 252 bp

>AT68668 NZ_CP018081:c318406-318155 [Sulfitobacter sp. AM1-D1]
ATGGCAAGCACAAGCGTCACACTTGGCCCCCATTGGGACGAATTCATCGCACTGATGTTGAAGGAGGGGCGCTACGGGTC
AACCAGCGAGTTGATCCGCGCCTCTTTGCGCCTGATGGAAGAGCAGGAAGGTCAGCGGGCGCGGCTTCGGGTTGCCTTGA
TGGAGGGCAAGCAATCCGGCGACGCTGGTCCGCTCGACATGGACGAAATCAAGCGCGAGGCGCGGAGCCGCTCCGGCGCT
TCTGATGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J0WPP0

Antitoxin

Source ID Structure
AlphaFold DB A0A225NCU8

References