Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 5147995..5148560 Replicon chromosome
Accession NZ_CP018063
Organism Rhodococcus sp. 2G

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BO226_RS24515 Protein ID WP_071936282.1
Coordinates 5148282..5148560 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BO226_RS24510 Protein ID WP_006551856.1
Coordinates 5147995..5148285 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BO226_RS24485 5143228..5143830 + 603 WP_019290064.1 TetR/AcrR family transcriptional regulator -
BO226_RS24490 5143827..5144255 + 429 WP_071936279.1 HIT family protein -
BO226_RS24495 5144260..5145861 + 1602 WP_071936280.1 L-lactate permease -
BO226_RS24500 5145938..5146966 + 1029 WP_071936281.1 Dyp-type peroxidase -
BO226_RS24505 5146963..5147781 + 819 WP_006551857.1 bacteriocin family protein -
BO226_RS24510 5147995..5148285 + 291 WP_006551856.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BO226_RS24515 5148282..5148560 + 279 WP_071936282.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BO226_RS24520 5148617..5149096 - 480 WP_006551854.1 MarR family transcriptional regulator -
BO226_RS24525 5149155..5149907 - 753 WP_064060432.1 cutinase family protein -
BO226_RS24530 5150057..5150719 - 663 WP_024102984.1 alpha-ketoglutarate-dependent dioxygenase AlkB -
BO226_RS24535 5150840..5151670 + 831 WP_006551851.1 SDR family oxidoreductase -
BO226_RS24540 5151714..5152685 + 972 WP_006551850.1 phosphotriesterase -
BO226_RS24545 5152722..5153441 - 720 WP_071936556.1 2OG-Fe(II) oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(40-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-73)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10296.83 Da        Isoelectric Point: 10.2459

>T68654 WP_071936282.1 NZ_CP018063:5148282-5148560 [Rhodococcus sp. 2G]
MSTPDHPYRLVMARSAARAMARSLPERVATAVYEFVTGPLLENPKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVE
VTAISHRADAYR

Download         Length: 279 bp

>T68654 NZ_CP018063:5148282-5148560 [Rhodococcus sp. 2G]
ATGAGCACTCCGGACCACCCGTATCGGCTGGTGATGGCGAGGTCGGCTGCACGCGCCATGGCGAGGTCGTTGCCGGAGAG
GGTAGCAACTGCGGTATACGAGTTCGTCACAGGACCCCTTCTCGAGAATCCGAAGCGGGTGGGGAAGCCGTTGAATCCGC
CTCTTGCGCCGGCGTACAGCGCCCGGCGAGGTGAATATCGCGTCCTGTATCTGATCGATGATGCGAACCGCACGGTCGAG
GTCACCGCGATTTCGCACCGTGCCGATGCGTATCGATAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10788.92 Da        Isoelectric Point: 4.2336

>AT68654 WP_006551856.1 NZ_CP018063:5147995-5148285 [Rhodococcus sp. 2G]
MYMTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVD
VQELTQLMRDARSSEE

Download         Length: 291 bp

>AT68654 NZ_CP018063:5147995-5148285 [Rhodococcus sp. 2G]
ATGTACATGACGACTCTTCCTGTTGCCGACGCGCGGGCGCAATTGTCACGACTGGTCGATGAGGCCGAGCGCACACACGA
GCGATTCGAGATCACCCGCAACGGGCACCGCGCCGCGGTGCTTCTCGGTGCCGACGATTACGACGCGATGCAGGAGACGA
TCGCGGTGTTGTCGGATACGGATCTGCTGCGGGCGCACGTCGAGGGCCGAACGGAGGTCGAGTCGGGAGACGTCGTCGAT
GTACAGGAATTGACGCAGCTGATGCGTGATGCTCGGTCGTCCGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References