Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 435321..435466 Replicon chromosome
Accession NZ_CP018056
Organism Klebsiella pneumoniae subsp. pneumoniae strain H11

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 435357..435459 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 435321..435466 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPH11_RS02010 430451..432511 + 2061 WP_004151449.1 oligopeptidase B -
KPH11_RS02015 432515..433174 - 660 WP_032425085.1 exodeoxyribonuclease X -
KPH11_RS02020 433253..433483 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KPH11_RS02025 433596..433970 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KPH11_RS02030 433974..434843 + 870 WP_099761193.1 copper homeostasis membrane protein CopD -
KPH11_RS02035 434860..435198 + 339 WP_016529031.1 YebY family protein -
- 435321..435466 - 146 - - Antitoxin
- 435357..435459 + 103 - - Toxin
KPH11_RS26530 435835..435978 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KPH11_RS02045 436083..437051 - 969 WP_004151446.1 VirK/YbjX family protein -
KPH11_RS02050 437208..437861 + 654 WP_038807473.1 protein-serine/threonine phosphatase -
KPH11_RS02055 437858..438049 - 192 WP_002911395.1 YebW family protein -
KPH11_RS02060 438147..438386 - 240 WP_002911393.1 YebV family protein -
KPH11_RS02065 438502..439935 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T68628 NZ_CP018056:435357-435459 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT68628 NZ_CP018056:c435466-435321 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References