Detailed information of TA system TA068540

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 3735163..3736067
• Replicon: chromosome
• Accession: NZ_CP018016
• Organism: Kosakonia radicincitans DSM 16656

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: Y71_RS18060
• Protein ID: WP_007374122.1
• Coordinates: 3735603..3736067 (+)
• Length: 155 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: Y71_RS18055
• Protein ID: WP_007374123.1
• Coordinates: 3735163..3735606 (+)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Y71_RS18035	3730213..3731979	+	1767	WP_007374126.1	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	-
Y71_RS18040	3731980..3733701	+	1722	WP_007374125.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-
Y71_RS18045	3733807..3734511	+	705	WP_007374124.1	leucyl/phenylalanyl-tRNA--protein transferase	-
Y71_RS18050	3734796..3735014	+	219	WP_001040187.1	translation initiation factor IF-1	-
Y71_RS18055	3735163..3735606	+	444	WP_007374123.1	DUF2384 domain-containing protein	Antitoxin
Y71_RS18060	3735603..3736067	+	465	WP_007374122.1	RES domain-containing protein	Toxin
Y71_RS18065	3736189..3738477	-	2289	WP_035885867.1	ATP-dependent Clp protease ATP-binding subunit ClpA	-
Y71_RS18070	3738509..3738829	-	321	WP_007374120.1	ATP-dependent Clp protease adapter ClpS	-
Y71_RS18075	3739158..3739379	+	222	WP_007374119.1	cold shock-like protein CspD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-148)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (29-90)

Sequences

Toxin

Protein

• Length: 155 a.a.
• Molecular weight: 17044.40 Da
• Isoelectric Point: 6.0751

>T68540 WP_007374122.1 NZ_CP018016:3735603-3736067 [Kosakonia radicincitans DSM 16656]
VIFYRLVSRRYASEAWTGSGANQYGGRWNHKGHPAVYIASSVSLAALEMLVHVRSDTILSQYGLFSIDIPDKEIEYLDKQ
WLPPDWQENPAPLSTMDLGTAWLEANSAVALVVPSCVIPLENNAILNPQHAGFSKLLKSVKELPFSFDARLASS

Nucleotide

• Length: 465 bp

>T68540 NZ_CP018016:3735603-3736067 [Kosakonia radicincitans DSM 16656]
GTGATTTTTTATCGCCTTGTGTCGCGCCGCTACGCCAGCGAAGCCTGGACCGGCAGCGGTGCGAATCAATATGGCGGCAG
ATGGAATCACAAAGGTCACCCGGCGGTTTATATTGCCTCATCCGTTTCCCTCGCCGCGCTGGAAATGCTGGTGCATGTAC
GCAGCGACACGATCCTTAGCCAGTACGGCCTGTTCAGTATCGACATTCCCGATAAAGAGATTGAATATCTGGATAAACAG
TGGCTGCCGCCGGACTGGCAGGAAAACCCGGCTCCGCTTTCAACGATGGATCTGGGAACCGCCTGGCTGGAAGCCAACAG
CGCCGTCGCGCTGGTAGTTCCTTCCTGCGTCATTCCTCTGGAAAACAATGCCATCCTCAATCCACAGCACGCTGGATTCA
GCAAGTTACTCAAATCAGTAAAAGAGCTTCCTTTTTCGTTTGATGCGCGTCTGGCTTCATCCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16407.90 Da
• Isoelectric Point: 9.9132

>AT68540 WP_007374123.1 NZ_CP018016:3735163-3735606 [Kosakonia radicincitans DSM 16656]
MRTWSPEQKPVENALWRFAGFPANRGIKLVQMLNEGLPVSILDNIHEWTEMSRSDILRVTGINERNVARRKSAGRTLTPE
ESERIARLVRVIDAAVQFFGDKKMAYAWLQAPVRGLGNVAPISLIATESGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT68540 NZ_CP018016:3735163-3735606 [Kosakonia radicincitans DSM 16656]
ATGAGAACCTGGAGCCCGGAACAAAAACCGGTTGAAAATGCACTCTGGCGTTTCGCCGGTTTCCCCGCTAACCGCGGTAT
AAAACTTGTTCAGATGTTGAATGAGGGTTTGCCTGTCAGCATTCTGGATAATATCCATGAGTGGACGGAGATGTCTCGCT
CCGACATCCTGCGTGTCACCGGTATTAACGAGCGCAATGTCGCCCGCCGTAAGAGCGCGGGACGCACCTTAACGCCGGAA
GAGAGCGAGCGGATCGCCCGCTTGGTTCGCGTGATCGACGCCGCCGTTCAGTTTTTTGGTGATAAAAAAATGGCGTACGC
CTGGCTGCAAGCGCCGGTACGCGGCCTCGGTAACGTTGCTCCTATCTCCCTGATTGCGACTGAAAGTGGCGCACTGGAAG
TCACCGATCTGATTGGCCGCCTGGAGCACGGAGTATTTGCGTGA