Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 188723..189303 Replicon plasmid pY9
Accession NZ_CP018001
Organism Rhizobium sp. Y9

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BLX90_RS24310 Protein ID WP_100911711.1
Coordinates 188723..189106 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BLX90_RS24315 Protein ID WP_044460077.1
Coordinates 189103..189303 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLX90_RS24275 184427..184717 - 291 WP_100911704.1 co-chaperone GroES -
BLX90_RS24280 185203..185430 - 228 WP_100911705.1 hypothetical protein -
BLX90_RS24290 185843..186196 - 354 WP_100911707.1 DUF1488 domain-containing protein -
BLX90_RS24295 186196..186456 - 261 WP_100911708.1 hypothetical protein -
BLX90_RS24300 186742..187656 - 915 WP_198523858.1 LysR family transcriptional regulator -
BLX90_RS24305 187763..188629 + 867 WP_100911710.1 aldo/keto reductase family oxidoreductase -
BLX90_RS24310 188723..189106 - 384 WP_100911711.1 type II toxin-antitoxin system VapC family toxin Toxin
BLX90_RS24315 189103..189303 - 201 WP_044460077.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
BLX90_RS24320 189513..189821 + 309 WP_100911712.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
BLX90_RS24325 189818..189985 + 168 Protein_194 type II toxin-antitoxin system RelE/ParE family toxin -
BLX90_RS24330 190154..190639 + 486 Protein_195 AAA family ATPase -
BLX90_RS24335 190802..192871 + 2070 WP_100911713.1 NAD(+) synthase -
BLX90_RS24340 192890..193489 + 600 WP_100911714.1 cysteine hydrolase -
BLX90_RS26140 193553..194278 - 726 Protein_198 Crp/Fnr family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd / htpB 1..481964 481964


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14116.33 Da        Isoelectric Point: 6.9166

>T68520 WP_100911711.1 NZ_CP018001:c189106-188723 [Rhizobium sp. Y9]
VILVDSSIWIDHFRHVEPELVKIIGDDQLLCHPFVVGELALGSLRERDAVLAFLTAQREAIVATHAEVMTVIDRHSIFSM
GIGYTDAHLLTSTLLDRRSSLWTRDKRLAAAARKAGAALYLSPHIPH

Download         Length: 384 bp

>T68520 NZ_CP018001:c189106-188723 [Rhizobium sp. Y9]
GTGATTCTTGTCGACAGTTCAATCTGGATTGATCATTTCCGACACGTCGAGCCGGAGCTAGTCAAAATCATCGGAGATGA
TCAGCTGCTTTGCCACCCTTTCGTTGTAGGTGAACTGGCCTTGGGTAGTCTGCGAGAACGGGATGCGGTATTAGCGTTTC
TCACAGCTCAGCGTGAAGCAATAGTTGCAACCCATGCAGAAGTGATGACAGTCATTGATCGCCATTCGATATTCAGCATG
GGGATCGGCTATACTGATGCACATTTGTTGACTTCAACTCTCCTGGACCGGCGATCCAGCTTATGGACTAGGGATAAGCG
CCTGGCGGCCGCCGCTCGGAAGGCTGGCGCGGCGCTTTATCTCTCTCCGCATATTCCTCATTAG

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7267.41 Da        Isoelectric Point: 11.0968

>AT68520 WP_044460077.1 NZ_CP018001:c189303-189103 [Rhizobium sp. Y9]
MRSTINLDDSLMERAKSLTGTKETAALVRQALETLVRVESGKRLIALGGTMPEAEAAPRRRSEVRK

Download         Length: 201 bp

>AT68520 NZ_CP018001:c189303-189103 [Rhizobium sp. Y9]
ATGCGATCAACCATCAATCTCGACGACAGCCTTATGGAAAGAGCAAAGTCCCTAACGGGCACGAAGGAAACGGCGGCTCT
TGTGCGTCAAGCACTGGAGACTTTGGTGCGAGTCGAGTCTGGCAAGCGGCTAATCGCTCTTGGAGGCACTATGCCTGAGG
CTGAGGCAGCGCCTCGCCGCCGGAGCGAAGTTAGGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References