Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 71416..71996 Replicon plasmid pY9
Accession NZ_CP018001
Organism Rhizobium sp. Y9

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BLX90_RS23730 Protein ID WP_100911653.1
Coordinates 71416..71799 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BLX90_RS23735 Protein ID WP_044460077.1
Coordinates 71796..71996 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLX90_RS23695 66722..67570 + 849 WP_044460071.1 alpha/beta hydrolase -
BLX90_RS23700 67636..68166 + 531 WP_044460072.1 VOC family protein -
BLX90_RS23705 68169..68897 + 729 WP_082055480.1 L,D-transpeptidase -
BLX90_RS23710 69007..69765 + 759 WP_044460074.1 alpha/beta hydrolase -
BLX90_RS23715 70006..70395 + 390 WP_020808332.1 RidA family protein -
BLX90_RS23720 70517..70948 - 432 WP_044460075.1 type II toxin-antitoxin system VapC family toxin -
BLX90_RS23730 71416..71799 - 384 WP_100911653.1 type II toxin-antitoxin system VapC family toxin Toxin
BLX90_RS23735 71796..71996 - 201 WP_044460077.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
BLX90_RS23740 72191..74551 - 2361 WP_044460078.1 hypothetical protein -
BLX90_RS23745 74701..75278 - 578 Protein_80 PIN domain-containing protein -
BLX90_RS23750 75268..75714 - 447 WP_044460079.1 excisionase -
BLX90_RS23755 75893..76375 - 483 Protein_82 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - gmd / htpB 1..481964 481964


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14172.44 Da        Isoelectric Point: 6.9168

>T68518 WP_100911653.1 NZ_CP018001:c71799-71416 [Rhizobium sp. Y9]
VILVDSSIWIDHFRHVEPELVKIIGDDQLLCHPFVVGELALVSLRERDAVLAFLTAQREAIVATHAEVMTVIDRHSIFSM
GIGYTDAHLLTSTLLERRSSLWTRDKRLAAAARKAGAALYLSPHIPH

Download         Length: 384 bp

>T68518 NZ_CP018001:c71799-71416 [Rhizobium sp. Y9]
GTGATTCTTGTCGACAGTTCAATCTGGATTGATCATTTCCGACACGTCGAGCCGGAGCTAGTCAAAATCATCGGAGATGA
TCAGCTGCTTTGCCACCCTTTCGTTGTAGGTGAACTGGCCTTGGTTAGTCTGCGAGAACGGGATGCGGTATTAGCGTTTC
TCACAGCTCAGCGTGAAGCAATAGTTGCAACCCATGCAGAAGTGATGACAGTCATTGATCGCCATTCGATATTCAGCATG
GGGATCGGCTATACTGATGCACATTTGTTGACTTCAACTCTCCTGGAGCGGCGATCCAGCTTATGGACGAGGGATAAGCG
CCTGGCGGCCGCCGCTCGGAAGGCTGGCGCGGCGCTTTATCTCTCTCCGCATATTCCTCATTAG

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7267.41 Da        Isoelectric Point: 11.0968

>AT68518 WP_044460077.1 NZ_CP018001:c71996-71796 [Rhizobium sp. Y9]
MRSTINLDDSLMERAKSLTGTKETAALVRQALETLVRVESGKRLIALGGTMPEAEAAPRRRSEVRK

Download         Length: 201 bp

>AT68518 NZ_CP018001:c71996-71796 [Rhizobium sp. Y9]
ATGCGATCAACCATCAATCTCGACGACAGCCTTATGGAAAGAGCAAAGTCCCTAACGGGCACGAAGGAAACGGCGGCTCT
TGTGCGTCAAGCACTGGAGACTTTGGTGCGAGTCGAGTCTGGCAAGCGGCTAATCGCTCTTGGAGGCACTATGCCTGAGG
CTGAGGCAGCGCCTCGCCGCCGGAGCGAAGTTAGGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References