Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 643407..643552 Replicon chromosome
Accession NZ_CP017994
Organism Klebsiella pneumoniae strain P1428

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 643414..643516 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 643407..643552 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BMF28_RS03290 638939..640372 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BMF28_RS03295 640488..640727 + 240 WP_002911393.1 YebV family protein -
BMF28_RS03300 640825..641016 + 192 WP_002911395.1 YebW family protein -
BMF28_RS03305 641013..641666 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
BMF28_RS03310 641823..642791 + 969 WP_014907334.1 VirK/YbjX family protein -
BMF28_RS27995 642896..643039 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 643407..643552 + 146 - - Antitoxin
- 643414..643516 - 103 - - Toxin
BMF28_RS03320 643675..644013 - 339 WP_002911404.1 YebY family protein -
BMF28_RS03325 644030..644899 - 870 WP_014907333.1 copper homeostasis membrane protein CopD -
BMF28_RS03330 644903..645277 - 375 WP_004151448.1 CopC domain-containing protein YobA -
BMF28_RS03335 645390..645620 + 231 WP_002911406.1 DNA polymerase III subunit theta -
BMF28_RS03340 645699..646358 + 660 WP_002911407.1 exodeoxyribonuclease X -
BMF28_RS03345 646362..648422 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T68495 NZ_CP017994:c643516-643414 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT68495 NZ_CP017994:643407-643552 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References