Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 268287..268918 Replicon chromosome
Accession NZ_CP017965
Organism Nocardiopsis dassonvillei strain NOCA502F

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag A9R04_RS01190 Protein ID WP_071621010.1
Coordinates 268287..268700 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag A9R04_RS01195 Protein ID WP_071623115.1
Coordinates 268697..268918 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9R04_RS01170 264030..264761 - 732 WP_013156383.1 WbqC family protein -
A9R04_RS01175 265110..266633 + 1524 WP_013156384.1 glycosyltransferase family 2 protein -
A9R04_RS01180 266775..267182 + 408 WP_013156385.1 DUF3817 domain-containing protein -
A9R04_RS01185 267158..267916 - 759 WP_071621009.1 SURF1 family protein -
A9R04_RS01190 268287..268700 - 414 WP_071621010.1 PIN domain-containing protein Toxin
A9R04_RS01195 268697..268918 - 222 WP_071623115.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
A9R04_RS01200 269004..269537 - 534 WP_071623116.1 DinB family protein -
A9R04_RS01205 269696..270463 + 768 WP_013156388.1 alpha/beta hydrolase -
A9R04_RS01210 270489..270896 - 408 WP_013156389.1 VOC family protein -
A9R04_RS01215 271166..271828 - 663 WP_071621011.1 class II aldolase/adducin family protein -
A9R04_RS01220 272158..273684 + 1527 WP_041553454.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-122)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(4-44)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15832.94 Da        Isoelectric Point: 6.7571

>T68402 WP_071621010.1 NZ_CP017965:c268700-268287 [Nocardiopsis dassonvillei]
VIRFLIDSSALWRVLRDEKYRLAWREVITEGAVGSCTVQRVEFRRSARNLDEYEQFNDMFEVLHPNVPVPKSAWQWVESA
QYRLLRAGAHRALSSVDLLIAATAAHHGLVVLHDDDDFATAARHLTDLRERRIQDIP

Download         Length: 414 bp

>T68402 NZ_CP017965:c268700-268287 [Nocardiopsis dassonvillei]
GTGATCCGGTTCCTGATCGACTCGTCCGCGCTGTGGCGTGTGCTCCGGGACGAGAAGTACAGGCTGGCCTGGCGTGAGGT
CATCACGGAAGGCGCCGTGGGCTCGTGCACCGTACAGCGTGTCGAGTTCCGTCGCTCCGCACGCAACCTCGACGAGTACG
AACAGTTCAACGACATGTTCGAGGTGCTCCACCCGAACGTCCCCGTGCCGAAGAGCGCCTGGCAGTGGGTGGAGTCCGCC
CAGTACCGACTCCTGCGCGCGGGCGCACACCGCGCGCTGTCGTCGGTGGACCTGCTCATCGCCGCCACGGCCGCCCACCA
CGGACTCGTCGTCCTCCATGACGACGACGACTTCGCGACGGCCGCGCGCCACCTCACCGACCTGAGGGAGCGCCGGATCC
AGGACATCCCCTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8565.60 Da        Isoelectric Point: 6.4697

>AT68402 WP_071623115.1 NZ_CP017965:c268918-268697 [Nocardiopsis dassonvillei]
MSLTQIDVDDEALQEAMRLSGTRTKKETVNLALREYARRHRRIAALEHFADLAKDWDYEGWKEQRAAAKEPYT

Download         Length: 222 bp

>AT68402 NZ_CP017965:c268918-268697 [Nocardiopsis dassonvillei]
ATGAGCCTGACCCAGATCGACGTCGACGACGAGGCGCTCCAAGAGGCCATGCGCCTGTCCGGCACGCGCACCAAGAAGGA
AACGGTGAACCTGGCCCTTCGGGAGTACGCGCGCAGACACCGGCGCATCGCGGCCCTGGAGCACTTCGCCGACCTGGCCA
AGGACTGGGACTACGAAGGCTGGAAAGAGCAGCGGGCGGCCGCGAAGGAGCCGTACACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References