Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 4517286..4517818 Replicon chromosome
Accession NZ_CP017946
Organism Bosea sp. Tri-49

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BLM15_RS21860 Protein ID WP_126114738.1
Coordinates 4517286..4517570 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BLM15_RS21865 Protein ID WP_126114739.1
Coordinates 4517567..4517818 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLM15_RS21835 4512904..4513722 + 819 WP_126114734.1 TPM domain-containing protein -
BLM15_RS21840 4513724..4514332 + 609 WP_126114735.1 hypothetical protein -
BLM15_RS21845 4514336..4515088 - 753 WP_126114736.1 DUF1223 domain-containing protein -
BLM15_RS21850 4515158..4516186 - 1029 WP_206438553.1 lipid A biosynthesis lauroyl acyltransferase -
BLM15_RS21855 4516250..4517272 - 1023 WP_126114737.1 zinc-binding dehydrogenase -
BLM15_RS21860 4517286..4517570 - 285 WP_126114738.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BLM15_RS21865 4517567..4517818 - 252 WP_126114739.1 ribbon-helix-helix protein, CopG family Antitoxin
BLM15_RS21870 4517917..4518663 - 747 WP_126114740.1 SDR family oxidoreductase -
BLM15_RS21875 4518660..4519943 - 1284 WP_126114741.1 beta-ketoacyl-ACP synthase -
BLM15_RS21880 4519955..4521085 - 1131 WP_126114742.1 beta-ketoacyl-ACP synthase -
BLM15_RS21885 4521087..4521548 - 462 WP_126114743.1 beta-hydroxyacyl-ACP dehydratase -
BLM15_RS21890 4521639..4521920 - 282 WP_057191987.1 acyl carrier protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-88)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10427.12 Da        Isoelectric Point: 10.9484

>T68395 WP_126114738.1 NZ_CP017946:c4517570-4517286 [Bosea sp. Tri-49]
MKLVWTARAKADLRAIALYVADFSPTAALALVRRLRSAAAQLVDYPHSGRAGRVEETRELVVAGTSYILPYRVRDGRVEI
LAVLHASRQWPGQL

Download         Length: 285 bp

>T68395 NZ_CP017946:c4517570-4517286 [Bosea sp. Tri-49]
ATGAAGCTCGTCTGGACCGCAAGAGCAAAGGCTGACCTTCGCGCTATCGCCCTCTATGTCGCCGACTTCAGTCCAACGGC
AGCGCTCGCCCTCGTCCGCCGGCTCCGCTCAGCCGCCGCCCAGTTGGTCGATTATCCGCATAGTGGCCGAGCCGGACGGG
TAGAAGAGACGCGTGAACTCGTGGTAGCCGGCACCAGCTACATCCTTCCCTATCGCGTCCGCGACGGACGCGTCGAAATC
CTCGCTGTCCTGCACGCCTCGCGGCAATGGCCGGGCCAGCTCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9309.35 Da        Isoelectric Point: 4.1319

>AT68395 WP_126114739.1 NZ_CP017946:c4517818-4517567 [Bosea sp. Tri-49]
MTAAFTIRLDDETLAKLDALAADTDRSRNWLAAKAIENYIELNAWQIARIKEGIAQADRGEFATEEELDAIEAELQARID
STR

Download         Length: 252 bp

>AT68395 NZ_CP017946:c4517818-4517567 [Bosea sp. Tri-49]
ATGACGGCCGCTTTCACGATCCGCCTCGACGACGAGACTCTCGCCAAACTCGACGCGTTGGCGGCAGATACCGATCGCTC
GCGCAACTGGCTCGCCGCCAAGGCGATCGAGAATTACATCGAACTCAATGCCTGGCAGATTGCCCGCATCAAGGAGGGCA
TCGCTCAGGCCGATCGTGGTGAATTCGCCACGGAGGAAGAGCTCGATGCGATCGAGGCGGAGCTGCAGGCACGCATCGAT
TCGACCAGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References