Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3082737..3083401 Replicon chromosome
Accession NZ_CP017946
Organism Bosea sp. Tri-49

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BLM15_RS15155 Protein ID WP_126113539.1
Coordinates 3082988..3083401 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BLM15_RS15150 Protein ID WP_126113538.1
Coordinates 3082737..3082991 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLM15_RS15130 3078027..3078872 + 846 WP_126113534.1 dienelactone hydrolase family protein -
BLM15_RS15135 3078895..3079623 - 729 WP_164547523.1 SGNH/GDSL hydrolase family protein -
BLM15_RS15140 3079780..3081303 - 1524 WP_126113536.1 exodeoxyribonuclease VII large subunit -
BLM15_RS15145 3081396..3082676 + 1281 WP_126113537.1 phosphoribosylamine--glycine ligase -
BLM15_RS15150 3082737..3082991 + 255 WP_126113538.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
BLM15_RS15155 3082988..3083401 + 414 WP_126113539.1 type II toxin-antitoxin system VapC family toxin Toxin
BLM15_RS15160 3083407..3084321 + 915 WP_126113540.1 alpha/beta hydrolase -
BLM15_RS15165 3084349..3085224 + 876 WP_126113541.1 patatin-like phospholipase family protein -
BLM15_RS15170 3085184..3085924 - 741 WP_126116191.1 ArsR family transcriptional regulator -
BLM15_RS15175 3086088..3086828 + 741 WP_126113542.1 sulfite exporter TauE/SafE family protein -
BLM15_RS15180 3086838..3087122 - 285 WP_164547524.1 DUF882 domain-containing protein -
BLM15_RS15185 3087613..3088116 - 504 WP_126113544.1 N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-125)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 14548.57 Da        Isoelectric Point: 4.2796

>T68394 WP_126113539.1 NZ_CP017946:3082988-3083401 [Bosea sp. Tri-49]
VTVQLVVDSSAIVAILTGEPEQAAFRARLDAAPKAFCSTASFVESFMVLSARIADLTADELQDALGTINVELLPFDAEQA
ILATQAFARFGKGRHPARLNLGDCFSYALAKSLNAPLLYKGEDFGLTDIATAVPSQE

Download         Length: 414 bp

>T68394 NZ_CP017946:3082988-3083401 [Bosea sp. Tri-49]
GTGACGGTCCAACTTGTCGTCGACAGCTCTGCGATCGTCGCGATCCTGACAGGCGAGCCGGAGCAAGCGGCGTTCCGTGC
TCGTCTCGATGCCGCGCCTAAGGCATTCTGCTCCACAGCGAGTTTCGTCGAAAGCTTCATGGTCTTGTCGGCCCGGATCG
CTGACTTGACTGCCGACGAGCTTCAAGACGCGCTGGGAACGATCAACGTCGAGCTGCTCCCGTTCGACGCCGAGCAGGCC
ATCTTGGCTACGCAAGCTTTTGCGCGCTTCGGCAAAGGCCGCCACCCGGCTCGCCTCAATCTCGGCGACTGCTTCTCCTA
CGCTCTTGCCAAATCCTTGAACGCGCCTCTGCTCTACAAGGGCGAGGATTTCGGCCTGACGGACATCGCCACGGCCGTAC
CGTCACAGGAGTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9358.60 Da        Isoelectric Point: 4.6604

>AT68394 WP_126113538.1 NZ_CP017946:3082737-3082991 [Bosea sp. Tri-49]
MTVLIKDSEADRLVRELAARTGETITQAVKIAAQERLDRLPPANGGRIDREKLDKLLAAFRDRLIVDPRSDDDIIGYDEN
GLPS

Download         Length: 255 bp

>AT68394 NZ_CP017946:3082737-3082991 [Bosea sp. Tri-49]
ATGACAGTGCTGATCAAAGATTCCGAAGCTGACCGGCTTGTCCGCGAGCTGGCCGCTCGGACCGGCGAGACTATTACCCA
AGCGGTCAAGATCGCCGCACAAGAGCGCTTGGACAGATTGCCGCCAGCAAATGGCGGCCGGATCGACCGCGAAAAGCTGG
ACAAGCTTCTGGCCGCATTCCGCGATCGGCTCATCGTCGATCCGCGATCCGACGACGACATCATCGGCTATGACGAAAAC
GGCCTGCCATCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References