Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 2378191..2378828 Replicon chromosome
Accession NZ_CP017946
Organism Bosea sp. Tri-49

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BLM15_RS11800 Protein ID WP_126112933.1
Coordinates 2378424..2378828 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BLM15_RS11795 Protein ID WP_126112932.1
Coordinates 2378191..2378427 (+) Length 79 a.a.

Genomic Context

BLM15_RS31355BLM15_RS11780BLM15_RS11790BLM15_RS11795BLM15_RS11800BLM15_RS11810BLM15_RS11815BLM15_RS11770BLM15_RS11775BLM15_RS11785BLM15_RS11805BLM15_RS11820BLM15_RS11825BLM15_RS11830BLM15_RS11835
Location: 2373502..2373651 (150 bp)
Type: Others
Protein ID: WP_164547487.1
Location: 2375387..2376907 (1521 bp)
Type: Others
Protein ID: WP_126112929.1
Location: 2377374..2378078 (705 bp)
Type: Others
Protein ID: WP_126112931.1
Location: 2378191..2378427 (237 bp)
Type: Antitoxin
Protein ID: WP_126112932.1
Location: 2378424..2378828 (405 bp)
Type: Toxin
Protein ID: WP_126112933.1
Location: 2380020..2380823 (804 bp)
Type: Others
Protein ID: WP_206438664.1
Location: 2380820..2381020 (201 bp)
Type: Others
Protein ID: WP_126112936.1
Location: 2373668..2374588 (921 bp)
Type: Others
Protein ID: WP_126112927.1
Location: 2374749..2375204 (456 bp)
Type: Others
Protein ID: WP_164547488.1
Location: 2376919..2377266 (348 bp)
Type: Others
Protein ID: WP_126112930.1
Location: 2378842..2379873 (1032 bp)
Type: Others
Protein ID: WP_126112934.1
Location: 2380977..2381444 (468 bp)
Type: Others
Protein ID: WP_126112937.1
Location: 2381456..2382289 (834 bp)
Type: Others
Protein ID: WP_126116146.1
Location: 2382421..2382928 (508 bp)
Type: Others
Protein ID: Protein_2351
Location: 2382954..2383454 (501 bp)
Type: Others
Protein ID: WP_126112938.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BLM15_RS313552373502..2373651+150WP_164547487.1hypothetical protein-
BLM15_RS117702373668..2374588-921WP_126112927.1AEC family transporter-
BLM15_RS117752374749..2375204-456WP_164547488.1thermonuclease family protein-
BLM15_RS117802375387..2376907+1521WP_126112929.1HAMP domain-containing histidine kinase-
BLM15_RS117852376919..2377266-348WP_126112930.1helix-turn-helix transcriptional regulator-
BLM15_RS117902377374..2378078+705WP_126112931.1glutathione S-transferase family protein-
BLM15_RS117952378191..2378427+237WP_126112932.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
BLM15_RS118002378424..2378828+405WP_126112933.1PIN domain-containing proteinToxin
BLM15_RS118052378842..2379873-1032WP_126112934.1nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase-
BLM15_RS118102380020..2380823+804WP_206438664.1adenosylcobinamide-GDP ribazoletransferase-
BLM15_RS118152380820..2381020+201WP_126112936.1DUF1289 domain-containing protein-
BLM15_RS118202380977..2381444-468WP_126112937.1GNAT family N-acetyltransferase-
BLM15_RS118252381456..2382289-834WP_126116146.1sulfite exporter TauE/SafE family protein-
BLM15_RS118302382421..2382928-508Protein_2351DsrE family protein-
BLM15_RS118352382954..2383454-501WP_126112938.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-115)

Antitoxin

SpoVT-AbrB domain

(5-43)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14876.77 Da        Isoelectric Point: 4.3689

>T68393 WP_126112933.1 NZ_CP017946:2378424-2378828 [Bosea sp. Tri-49]
VTRAFLDSNVVIYAFSDDPRNSVAEDLLGRGCELSVQVLNEFTNVARRKLGFSWAEITDAVEAITTLSRIVHPLGFATHQ
EAVRLAERYGLGFYDTLIVASALQSGCAVLYSEDMQHALIVDEQLRIENPFQAE

Download         Length: 405 bp

>T68393 NZ_CP017946:2378424-2378828 [Bosea sp. Tri-49]
GTGACGCGCGCCTTTCTCGACAGCAATGTGGTGATCTACGCCTTCAGCGACGATCCACGGAACTCTGTGGCAGAGGATCT
GCTTGGCCGCGGCTGCGAGCTCAGCGTCCAGGTCCTGAACGAATTCACCAATGTTGCGCGCCGCAAGCTGGGCTTCTCAT
GGGCGGAGATCACTGACGCGGTCGAGGCGATCACGACGCTCAGCCGCATCGTCCATCCGCTCGGTTTCGCCACGCACCAA
GAGGCCGTCAGGCTGGCCGAGCGCTACGGATTGGGCTTCTACGACACATTGATCGTAGCGAGCGCGCTACAATCGGGCTG
TGCGGTGCTCTACAGCGAAGACATGCAGCACGCCCTGATCGTCGACGAGCAGCTGAGGATCGAGAATCCGTTCCAGGCGG
AGTAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8919.24 Da        Isoelectric Point: 10.9040

>AT68393 WP_126112932.1 NZ_CP017946:2378191-2378427 [Bosea sp. Tri-49]
MQVARWGNSLAIRIPAAVSEALALKEGDDVDIRIADDRTFLIARDERKPRALARIRSLRKPLPPGWRFDRDEANERVP

Download         Length: 237 bp

>AT68393 NZ_CP017946:2378191-2378427 [Bosea sp. Tri-49]
ATGCAGGTCGCACGCTGGGGCAACAGCCTCGCCATTCGGATACCAGCGGCCGTCAGCGAGGCACTGGCGCTCAAGGAAGG
CGATGACGTCGATATCCGTATCGCGGACGATCGCACCTTCCTGATCGCGCGCGACGAGCGCAAGCCGCGCGCGCTCGCCC
GTATCCGCAGCCTGCGCAAGCCGCTCCCGCCCGGCTGGCGCTTCGATCGCGACGAGGCCAATGAGCGCGTCCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References