Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 253057..253573 Replicon plasmid unnamed4
Accession NZ_CP017944
Organism Phyllobacterium zundukense strain Tri-48

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag BLM14_RS29635 Protein ID WP_100003619.1
Coordinates 253292..253573 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BLM14_RS29630 Protein ID WP_100003618.1
Coordinates 253057..253302 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLM14_RS29600 248906..249919 + 1014 WP_100003612.1 fumarylacetoacetate hydrolase family protein -
BLM14_RS29605 249909..250556 + 648 WP_100003613.1 maleylacetoacetate isomerase -
BLM14_RS29610 250600..250977 - 378 WP_100003614.1 type II toxin-antitoxin system VapC family toxin -
BLM14_RS29615 250974..251201 - 228 WP_100003615.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
BLM14_RS29620 251267..252379 - 1113 WP_100003616.1 4-hydroxyphenylpyruvate dioxygenase -
BLM14_RS29625 252501..252962 + 462 WP_100003617.1 Lrp/AsnC family transcriptional regulator -
BLM14_RS29630 253057..253302 + 246 WP_100003618.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BLM14_RS29635 253292..253573 + 282 WP_100003619.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BLM14_RS29640 253570..254286 - 717 WP_100003620.1 ligase-associated DNA damage response endonuclease PdeM -
BLM14_RS29645 254283..256802 - 2520 WP_100003682.1 ligase-associated DNA damage response DEXH box helicase -
BLM14_RS29650 256911..257927 + 1017 WP_204252060.1 ligase-associated DNA damage response exonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..286438 286438


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10910.83 Da        Isoelectric Point: 10.9186

>T68391 WP_100003619.1 NZ_CP017944:253292-253573 [Phyllobacterium zundukense]
MSFKLEFLPSARKEWDKLGATIRQQFVKKLKERLDAPRIPSAALHGMPDHYKIKLRQAGYRLVYRVDDETITIIVVAVGK
RERNAVYERAKKR

Download         Length: 282 bp

>T68391 NZ_CP017944:253292-253573 [Phyllobacterium zundukense]
ATGAGCTTTAAGCTCGAATTCCTGCCTTCGGCGCGGAAGGAATGGGACAAACTTGGAGCCACCATACGCCAGCAATTTGT
CAAAAAGCTGAAAGAACGGCTTGATGCTCCGCGTATTCCAAGCGCGGCGCTGCATGGCATGCCCGATCACTACAAGATCA
AGCTGCGTCAGGCCGGCTACCGGCTGGTTTATCGCGTAGATGACGAGACCATAACAATTATCGTTGTCGCAGTGGGGAAA
CGAGAGCGCAATGCAGTCTACGAACGCGCCAAGAAACGTTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8863.08 Da        Isoelectric Point: 4.1059

>AT68391 WP_100003618.1 NZ_CP017944:253057-253302 [Phyllobacterium zundukense]
MQRVEAPVAVSVSDLKKSPTAIMNEANGEAVAVLNHNRIMAYMVPADVYEAMLDRLDDLHLAEIIESRSGEEGVPVDINE
L

Download         Length: 246 bp

>AT68391 NZ_CP017944:253057-253302 [Phyllobacterium zundukense]
ATGCAGCGTGTCGAAGCTCCGGTCGCCGTGAGCGTGTCCGACCTCAAAAAGAGCCCCACGGCCATCATGAATGAAGCAAA
TGGCGAGGCTGTGGCAGTGCTCAACCATAATCGGATTATGGCTTACATGGTCCCGGCAGACGTCTATGAAGCCATGCTCG
ATCGGCTTGATGATCTCCATCTTGCTGAAATCATCGAATCTCGCTCCGGCGAAGAGGGTGTTCCGGTCGACATCAATGAG
CTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References