Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 581907..582454 Replicon plasmid unnamed1
Accession NZ_CP017941
Organism Phyllobacterium zundukense strain Tri-48

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BLM14_RS22735 Protein ID WP_100002107.1
Coordinates 582161..582454 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag BLM14_RS22730 Protein ID WP_100002208.1
Coordinates 581907..582161 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLM14_RS22710 577264..577569 - 306 WP_100002103.1 hypothetical protein -
BLM14_RS22715 578007..579875 + 1869 WP_100002104.1 adenylate/guanylate cyclase domain-containing protein -
BLM14_RS22720 580064..580495 - 432 WP_100002105.1 dihydrofolate reductase -
BLM14_RS22725 580705..581472 + 768 WP_100002106.1 Stf0 sulfotransferase -
BLM14_RS22730 581907..582161 + 255 WP_100002208.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
BLM14_RS22735 582161..582454 + 294 WP_100002107.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BLM14_RS22740 582947..583225 + 279 WP_100002108.1 metal/formaldehyde-sensitive transcriptional repressor -
BLM14_RS22745 583222..584166 + 945 WP_100002109.1 CDF family Co(II)/Ni(II) efflux transporter DmeF -
BLM14_RS22750 584348..584890 + 543 WP_100002110.1 chromate resistance protein ChrB -
BLM14_RS22755 584914..586131 + 1218 WP_100002209.1 MFS transporter -
BLM14_RS22760 586184..586369 - 186 WP_100002111.1 hypothetical protein -
BLM14_RS22765 586529..586777 - 249 WP_100002112.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..640058 640058


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(3-70)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11209.82 Da        Isoelectric Point: 5.5474

>T68390 WP_100002107.1 NZ_CP017941:582161-582454 [Phyllobacterium zundukense]
MRFSLSVEAEEDIIVITEQGIRMFGSLQARRYHDDLFAVLELIAANPRMAREREEISPPVRIHPFKAHLIVYRIEENGTI
FVIRIGHGHEDWASEPA

Download         Length: 294 bp

>T68390 NZ_CP017941:582161-582454 [Phyllobacterium zundukense]
ATGCGTTTTAGCCTTTCTGTCGAAGCGGAAGAGGACATCATTGTCATCACCGAGCAAGGTATCCGGATGTTCGGATCTCT
ACAGGCTAGGCGGTACCATGACGACTTGTTCGCGGTACTTGAACTGATCGCCGCGAATCCCCGAATGGCTCGTGAGCGAG
AAGAGATTTCGCCGCCGGTTAGGATCCATCCGTTCAAAGCCCATCTGATTGTCTACCGTATCGAAGAGAATGGAACCATT
TTCGTGATCCGAATAGGCCATGGACATGAAGATTGGGCCAGCGAACCTGCTTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9295.39 Da        Isoelectric Point: 10.2106

>AT68390 WP_100002208.1 NZ_CP017941:581907-582161 [Phyllobacterium zundukense]
MATMNVSLPDPMKDWVEAQARTGRYSNASDYVRDLIRRDQTRSDKIAAMQRFVDDGLKSGVGGRSKDELFAAAAARTETA
RGSR

Download         Length: 255 bp

>AT68390 NZ_CP017941:581907-582161 [Phyllobacterium zundukense]
ATGGCTACTATGAACGTGTCTCTACCGGACCCAATGAAAGATTGGGTCGAAGCCCAAGCAAGGACCGGGCGATATTCCAA
TGCTAGTGACTATGTGCGCGACCTGATTCGAAGGGACCAAACGCGTAGTGATAAGATTGCTGCCATGCAACGCTTCGTCG
ATGACGGTCTCAAAAGTGGTGTTGGCGGCCGATCGAAGGACGAACTCTTCGCCGCGGCTGCCGCGCGCACGGAAACGGCG
CGCGGCAGCAGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References