Detailed information of TA system TA068389

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 3314271..3314736
• Replicon: chromosome
• Accession: NZ_CP017940
• Organism: Phyllobacterium zundukense strain Tri-48

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BLM14_RS16660
• Protein ID: WP_100000415.1
• Coordinates: 3314271..3314534 (+)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BLM14_RS16665
• Protein ID: WP_100000416.1
• Coordinates: 3314521..3314736 (+)
• Length: 72 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BLM14_RS16645	3310175..3311242	-	1068	WP_100000413.1	ABC transporter permease	-
BLM14_RS16650	3311270..3312877	-	1608	WP_100001413.1	ABC transporter substrate-binding protein	-
BLM14_RS16655	3312918..3313988	-	1071	WP_100000414.1	dipeptidase	-
BLM14_RS16660	3314271..3314534	+	264	WP_100000415.1	BrnT family toxin	Toxin
BLM14_RS16665	3314521..3314736	+	216	WP_100000416.1	CopG family transcriptional regulator	Antitoxin
BLM14_RS16670	3314802..3317243	-	2442	WP_100000417.1	DNA topoisomerase (ATP-hydrolyzing) subunit B	-
BLM14_RS16675	3317515..3319500	-	1986	WP_157929547.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-80)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10272.76 Da
• Isoelectric Point: 8.0521

>T68389 WP_100000415.1 NZ_CP017940:3314271-3314534 [Phyllobacterium zundukense]
MLFEYDPAKSASNKIKHGIDFEEAQSLWKDERMLEAPAKLDGEPRFLVIGLLRGKHWSAICVHRSDKVRIISVRRARRQE
IEYYENE

Nucleotide

• Length: 264 bp

>T68389 NZ_CP017940:3314271-3314534 [Phyllobacterium zundukense]
ATGCTGTTTGAGTACGATCCGGCAAAGAGCGCGTCCAATAAAATCAAACACGGTATTGATTTTGAGGAAGCACAATCGCT
CTGGAAAGATGAACGGATGCTGGAAGCTCCAGCCAAATTGGATGGAGAGCCGCGTTTTCTCGTAATTGGCTTACTCAGAG
GCAAGCATTGGTCAGCAATATGCGTTCACAGAAGCGATAAGGTTCGCATCATTTCGGTTCGCCGGGCCCGAAGACAGGAA
ATCGAATACTATGAAAACGAGTGA

Antitoxin

Protein

• Length: 72 a.a.
• Molecular weight: 8326.45 Da
• Isoelectric Point: 6.3279

>AT68389 WP_100000416.1 NZ_CP017940:3314521-3314736 [Phyllobacterium zundukense]
MKTSDFDRNFDEGADIAEQVDWSKARRPNEELKRVNVDFPIWVVEGLDRQARRLGVTRQALIKLWIAERLG

Nucleotide

• Length: 216 bp

>AT68389 NZ_CP017940:3314521-3314736 [Phyllobacterium zundukense]
ATGAAAACGAGTGATTTTGACCGCAATTTCGACGAGGGGGCAGATATTGCCGAACAGGTGGATTGGTCGAAGGCCCGCCG
GCCCAACGAAGAACTCAAGCGGGTAAATGTCGACTTTCCCATATGGGTAGTGGAAGGTCTGGACAGACAGGCCCGGCGGC
TTGGCGTGACCCGACAAGCCCTTATCAAGCTCTGGATCGCCGAACGTCTGGGTTAG