Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2584485..2585149 Replicon chromosome
Accession NZ_CP017940
Organism Phyllobacterium zundukense strain Tri-48

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BLM14_RS13015 Protein ID WP_099999742.1
Coordinates 2584742..2585149 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BLM14_RS13010 Protein ID WP_099999741.1
Coordinates 2584485..2584745 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLM14_RS12985 2579851..2580102 + 252 WP_099999736.1 hypothetical protein -
BLM14_RS12990 2580773..2581543 - 771 WP_099999737.1 ABC transporter ATP-binding protein -
BLM14_RS12995 2581751..2582551 - 801 WP_099999738.1 ABC transporter ATP-binding protein -
BLM14_RS13000 2582548..2583375 - 828 WP_099999739.1 ABC transporter permease -
BLM14_RS13005 2583372..2584352 - 981 WP_099999740.1 ABC transporter permease -
BLM14_RS13010 2584485..2584745 + 261 WP_099999741.1 antitoxin Antitoxin
BLM14_RS13015 2584742..2585149 + 408 WP_099999742.1 type II toxin-antitoxin system VapC family toxin Toxin
BLM14_RS13020 2585168..2586784 - 1617 WP_099999743.1 ABC transporter substrate-binding protein -
BLM14_RS13025 2586803..2587894 - 1092 WP_100001295.1 alanine--glyoxylate aminotransferase family protein -
BLM14_RS13030 2588203..2589081 - 879 WP_099999744.1 transglutaminase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

SpoVT-AbrB domain

(10-44)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15219.62 Da        Isoelectric Point: 4.9567

>T68387 WP_099999742.1 NZ_CP017940:2584742-2585149 [Phyllobacterium zundukense]
MMRYVLDTNAVIQLVSRKSDGLVRLILEKREGEIGISSVVAHELYFGVYKSQKISFNLEALRLLLLDFPILEFDQEDARV
SGELRSTLAQAGLPIGPYDVLIAGQAKARDLIVITNNVREFQRVEGLKVEDWTTI

Download         Length: 408 bp

>T68387 NZ_CP017940:2584742-2585149 [Phyllobacterium zundukense]
ATGATGCGCTATGTGCTTGATACCAATGCTGTAATTCAATTGGTCTCGCGGAAATCGGACGGCCTGGTTCGCCTCATCCT
TGAGAAGCGCGAGGGGGAGATTGGTATCTCTTCGGTCGTCGCGCATGAGCTCTACTTCGGTGTCTATAAGAGCCAAAAGA
TTTCCTTCAACTTGGAAGCTCTCCGCCTGCTTCTTCTCGATTTTCCCATTTTGGAGTTCGATCAGGAAGACGCGCGTGTA
TCGGGAGAGCTGCGCAGCACGCTGGCACAGGCCGGCCTGCCCATAGGGCCTTACGATGTGCTCATCGCGGGCCAGGCAAA
AGCCCGCGACCTGATTGTCATAACCAACAATGTTCGCGAGTTTCAAAGGGTGGAGGGCCTGAAGGTCGAAGACTGGACCA
CCATCTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9666.94 Da        Isoelectric Point: 6.4683

>AT68387 WP_099999741.1 NZ_CP017940:2584485-2584745 [Phyllobacterium zundukense]
MPQIAKVFNSGNSQAVRLPKEFRLNVEEVEISREGDALILRPHKVEKQPWSSLKAALDHGFSPDFLNGGRDQPAAQERPE
LDALFK

Download         Length: 261 bp

>AT68387 NZ_CP017940:2584485-2584745 [Phyllobacterium zundukense]
ATGCCGCAGATTGCAAAAGTATTTAACTCCGGGAATTCGCAGGCTGTACGCCTGCCGAAGGAATTCCGTTTGAATGTCGA
GGAAGTTGAAATTTCGCGCGAGGGCGATGCTCTCATCCTGCGTCCCCACAAGGTCGAAAAGCAGCCATGGAGTTCGCTCA
AAGCGGCCCTCGATCATGGCTTCAGCCCAGACTTTCTGAACGGCGGTCGAGATCAACCCGCAGCGCAGGAGCGGCCGGAA
TTGGACGCTTTGTTCAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References