Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1787742..1788319 Replicon chromosome
Accession NZ_CP017940
Organism Phyllobacterium zundukense strain Tri-48

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag BLM14_RS08840 Protein ID WP_100001147.1
Coordinates 1788029..1788319 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag BLM14_RS08835 Protein ID WP_099999029.1
Coordinates 1787742..1788026 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLM14_RS08805 1782849..1783646 - 798 WP_099999023.1 TatD family hydrolase -
BLM14_RS08810 1783653..1785200 - 1548 WP_099999024.1 methionine--tRNA ligase -
BLM14_RS08815 1785299..1785682 - 384 WP_099999025.1 type II toxin-antitoxin system VapC family toxin -
BLM14_RS08820 1785682..1785939 - 258 WP_204251998.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
BLM14_RS08825 1785980..1787032 - 1053 WP_099999027.1 DNA polymerase III subunit delta' -
BLM14_RS08830 1787029..1787700 - 672 WP_099999028.1 dTMP kinase -
BLM14_RS08835 1787742..1788026 - 285 WP_099999029.1 putative addiction module antidote protein Antitoxin
BLM14_RS08840 1788029..1788319 - 291 WP_100001147.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BLM14_RS08845 1788377..1789588 - 1212 WP_100001148.1 D-alanyl-D-alanine carboxypeptidase -
BLM14_RS08850 1789575..1790843 - 1269 WP_100001150.1 septal ring lytic transglycosylase RlpA family protein -
BLM14_RS08860 1791724..1792020 + 297 WP_099999030.1 hypothetical protein -
BLM14_RS08870 1792848..1793108 - 261 WP_099999032.1 DUF982 domain-containing protein -
BLM14_RS08875 1793149..1793319 - 171 WP_157929504.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-89)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10738.42 Da        Isoelectric Point: 10.3123

>T68386 WP_100001147.1 NZ_CP017940:c1788319-1788029 [Phyllobacterium zundukense]
MVEIRQTLEFASWLTALKDTNAIARIQVRIRRLSLGNPGDVKPIGEGVSELRVDYGPGYRIYYQKRGQTLVLLLCGGDKR
TQTADTARAKALAKEF

Download         Length: 291 bp

>T68386 NZ_CP017940:c1788319-1788029 [Phyllobacterium zundukense]
ATGGTCGAAATTCGTCAAACGCTCGAATTTGCCAGTTGGCTCACAGCACTGAAGGATACAAATGCGATTGCGCGTATTCA
GGTTAGAATTCGACGCCTGTCACTTGGTAATCCGGGCGATGTGAAGCCAATCGGGGAAGGGGTCAGTGAGCTTCGGGTCG
ATTACGGACCTGGTTACAGAATTTACTACCAGAAGCGTGGCCAGACCCTGGTGTTGCTATTGTGTGGCGGCGACAAGCGC
ACACAGACTGCCGATACTGCCAGGGCCAAAGCACTAGCAAAGGAGTTCTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 9855.21 Da        Isoelectric Point: 4.3855

>AT68386 WP_099999029.1 NZ_CP017940:c1788026-1787742 [Phyllobacterium zundukense]
MALVTKPWDVTENLDSPEAIVAYVEAAFEDGDPALIAAVIGDVARARGMTQLARDAGVSRETIYKAFSEGGNPTLETLTG
VIRALGLKLSVHAA

Download         Length: 285 bp

>AT68386 NZ_CP017940:c1788026-1787742 [Phyllobacterium zundukense]
ATGGCACTTGTAACAAAACCATGGGATGTCACGGAGAATCTGGATAGCCCGGAAGCCATTGTGGCCTATGTCGAAGCCGC
GTTTGAGGATGGTGATCCTGCCCTTATTGCTGCCGTTATCGGAGATGTCGCGCGCGCTCGTGGAATGACACAGCTGGCCC
GAGACGCCGGTGTAAGCCGGGAGACGATCTACAAGGCGTTTAGCGAGGGTGGAAACCCAACCCTTGAAACGCTTACCGGG
GTCATACGAGCCCTTGGTCTGAAACTGTCTGTGCATGCTGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References