Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 398171..398824 Replicon chromosome
Accession NZ_CP017938
Organism Acinetobacter pittii strain YMC2010/8/T346

Toxin (Protein)


Gene name cptA Uniprot ID A0A1A0GD63
Locus tag BMU11_RS01820 Protein ID WP_064786467.1
Coordinates 398171..398560 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A009HHW9
Locus tag BMU11_RS01825 Protein ID WP_002117064.1
Coordinates 398567..398824 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BMU11_RS01805 393277..395472 - 2196 WP_078219737.1 TRAP transporter large permease subunit -
BMU11_RS01810 395652..396227 - 576 WP_134854226.1 rhombosortase -
BMU11_RS01815 396312..397400 - 1089 WP_014207738.1 hypothetical protein -
BMU11_RS01820 398171..398560 - 390 WP_064786467.1 hypothetical protein Toxin
BMU11_RS01825 398567..398824 - 258 WP_002117064.1 succinate dehydrogenase assembly factor 2 Antitoxin
BMU11_RS01830 399013..400185 + 1173 WP_016143559.1 acyl-CoA dehydrogenase family protein -
BMU11_RS01835 400236..401726 - 1491 WP_069141217.1 NAD(P)/FAD-dependent oxidoreductase -
BMU11_RS01840 401908..402285 - 378 WP_002049717.1 50S ribosomal protein L17 -
BMU11_RS01845 402304..403311 - 1008 WP_002116730.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15506.55 Da        Isoelectric Point: 6.3102

>T68384 WP_064786467.1 NZ_CP017938:c398560-398171 [Acinetobacter pittii]
MIKELNFELKYSRVSVIFQLFVGLGLAILLYQLLTPIWWLCAVVLLFIGFIFFLKQAQISQIEYLDQKLWSVAYFSEKEI
YRAEITKIIDYQLFVVIYLEETPTNIAIVWFDQLPIQQWKRLKVLEKLY

Download         Length: 390 bp

>T68384 NZ_CP017938:c398560-398171 [Acinetobacter pittii]
TTGATAAAAGAATTAAATTTTGAGCTGAAATATAGCCGAGTCTCGGTAATATTTCAGCTTTTTGTTGGTTTGGGTTTAGC
AATCTTGCTTTATCAATTATTAACGCCGATATGGTGGCTATGTGCTGTCGTTCTTCTATTTATTGGTTTTATTTTCTTTT
TAAAGCAAGCACAAATATCTCAAATTGAATATTTAGATCAAAAATTATGGTCGGTTGCATATTTCTCGGAAAAAGAAATT
TACCGTGCAGAAATTACTAAAATAATTGATTATCAGTTATTTGTAGTTATTTATCTTGAAGAAACTCCTACGAACATAGC
TATTGTTTGGTTCGATCAGCTTCCTATTCAGCAGTGGAAAAGATTAAAAGTTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10295.73 Da        Isoelectric Point: 4.4809

>AT68384 WP_002117064.1 NZ_CP017938:c398824-398567 [Acinetobacter pittii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Download         Length: 258 bp

>AT68384 NZ_CP017938:c398824-398567 [Acinetobacter pittii]
ATGTCTGACGAAATGACCTTGGAAGAACGTAAAGTAATTTATCGAGCACGCCGCGGCTTAAAAGAAATTGACGTCTATTT
TGACCCGTATGTAAAAAATTATTATTTAAAAGCTGATCCAGCAGAAAAAGCATTATTTGCAGAGCTAGTTGATCAAGAAG
ATCCAGATTTATTAGATTGGTTCATGGAAGTTTCTGAACCTCCACGTACTGAGTTACGTGAATTTATTTATAAACTAAAA
CAGTATGTGCATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A0GD63

Antitoxin

Source ID Structure
AlphaFold DB A0A009HHW9

References