Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5345212..5345357 Replicon chromosome
Accession NZ_CP017934
Organism Klebsiella pneumoniae strain CAV1016

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5345248..5345350 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5345212..5345357 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AGE75_RS26465 5340342..5342402 + 2061 WP_032419805.1 oligopeptidase B -
AGE75_RS26470 5342406..5343065 - 660 WP_002911407.1 exodeoxyribonuclease X -
AGE75_RS26475 5343144..5343374 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AGE75_RS26480 5343487..5343861 + 375 WP_020316569.1 CopC domain-containing protein YobA -
AGE75_RS26485 5343865..5344734 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AGE75_RS26490 5344751..5345089 + 339 WP_002911404.1 YebY family protein -
- 5345212..5345357 - 146 - - Antitoxin
- 5345248..5345350 + 103 - - Toxin
AGE75_RS29970 5345725..5345868 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AGE75_RS26500 5345973..5346941 - 969 WP_014907334.1 VirK/YbjX family protein -
AGE75_RS26505 5347098..5347751 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
AGE75_RS26510 5347748..5347939 - 192 WP_002911395.1 YebW family protein -
AGE75_RS26515 5348037..5348276 - 240 WP_002911393.1 YebV family protein -
AGE75_RS26520 5348392..5349825 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T68375 NZ_CP017934:5345248-5345350 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT68375 NZ_CP017934:c5345357-5345212 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References