Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 38759..39287 Replicon plasmid pL291
Accession NZ_CP017909
Organism Vibrio alginolyticus strain K06K5

Toxin (Protein)


Gene name relE Uniprot ID A0A1W6UUU0
Locus tag K06K5_RS25215 Protein ID WP_025767362.1
Coordinates 39003..39287 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K06K5_RS25210 Protein ID WP_086048372.1
Coordinates 38759..39013 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K06K5_RS25175 34088..34462 - 375 WP_025767354.1 hypothetical protein -
K06K5_RS25180 34643..35473 - 831 WP_086048366.1 hypothetical protein -
K06K5_RS26960 35620..35796 - 177 WP_157664648.1 hypothetical protein -
K06K5_RS25185 35807..36400 - 594 WP_086048367.1 hypothetical protein -
K06K5_RS25190 36578..36949 + 372 WP_157666753.1 hypothetical protein -
K06K5_RS25195 36998..37231 - 234 WP_086048369.1 hypothetical protein -
K06K5_RS25200 37250..37684 - 435 WP_086048370.1 hypothetical protein -
K06K5_RS25205 37750..38502 - 753 WP_086048371.1 hypothetical protein -
K06K5_RS25210 38759..39013 + 255 WP_086048372.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
K06K5_RS25215 39003..39287 + 285 WP_025767362.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K06K5_RS25225 39524..39712 + 189 WP_025767364.1 hypothetical protein -
K06K5_RS25230 39725..39988 + 264 WP_025767365.1 hypothetical protein -
K06K5_RS25235 40223..40543 - 321 WP_086048373.1 hypothetical protein -
K06K5_RS25240 40795..41541 + 747 WP_025767367.1 hypothetical protein -
K06K5_RS25245 42776..43084 + 309 WP_086048374.1 hypothetical protein -
K06K5_RS25250 43382..43702 + 321 WP_086048375.1 hypothetical protein -
K06K5_RS25255 43712..43915 + 204 WP_025767370.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..291285 291285


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-84)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 95 a.a.        Molecular weight: 11103.10 Da        Isoelectric Point: 10.6691

>T68275 WP_025767362.1 NZ_CP017909:39003-39287 [Vibrio alginolyticus]
MTYKLVFKTEAEKEWRKLDSTIKSQFKKKLIERLENPHVPTAKLSSMENCYKIKLRSAGYRLVYQVRDQEVIISVVAVGK
RERNQVYKIAAKRV

Download         Length: 285 bp

>T68275 NZ_CP017909:39003-39287 [Vibrio alginolyticus]
ATGACTTATAAGTTAGTTTTCAAGACTGAGGCAGAGAAAGAATGGCGCAAGTTGGACAGCACTATTAAGTCTCAGTTTAA
GAAGAAGCTGATTGAACGTTTAGAAAATCCGCATGTACCAACGGCAAAATTAAGCAGTATGGAGAATTGCTACAAAATAA
AACTGAGAAGTGCAGGATACCGGCTTGTTTATCAAGTGAGAGATCAGGAAGTAATTATTTCAGTTGTGGCAGTTGGTAAG
CGAGAACGTAATCAGGTTTATAAAATCGCTGCAAAAAGAGTGTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9474.81 Da        Isoelectric Point: 3.9953

>AT68275 WP_086048372.1 NZ_CP017909:38759-39013 [Vibrio alginolyticus]
MPTIRPILADNSTSISELKKNPMAVIEQADGFPVAVLNRNQPAFYCVPADAYEMLMDKLEDIELAQIVKEREHSEEIEIS
IDDL

Download         Length: 255 bp

>AT68275 NZ_CP017909:38759-39013 [Vibrio alginolyticus]
ATGCCAACAATTCGTCCTATTCTCGCTGATAATTCAACAAGTATCAGCGAACTTAAAAAGAACCCTATGGCAGTCATAGA
ACAAGCTGACGGGTTCCCTGTTGCGGTACTGAACCGTAATCAACCTGCATTTTACTGCGTTCCTGCGGATGCCTATGAAA
TGCTCATGGATAAACTGGAAGATATTGAGCTTGCTCAGATAGTTAAAGAGCGTGAGCATTCTGAAGAAATAGAGATCAGC
ATCGATGACTTATAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A1W6UUU0


Antitoxin

Source ID Structure

References