Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VagC |
Location | 2604412..2605049 | Replicon | chromosome |
Accession | NZ_CP017886 | ||
Organism | Pseudomonas frederiksbergensis strain ERDD5:01 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | A0A1J0EK94 |
Locus tag | BLL42_RS12605 | Protein ID | WP_071552388.1 |
Coordinates | 2604642..2605049 (+) | Length | 136 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | A0A1J0EKV4 |
Locus tag | BLL42_RS12600 | Protein ID | WP_054595147.1 |
Coordinates | 2604412..2604642 (+) | Length | 77 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BLL42_RS12570 | 2599510..2600592 | + | 1083 | WP_071552382.1 | hypothetical protein | - |
BLL42_RS12575 | 2600711..2601502 | + | 792 | WP_071552383.1 | TSUP family transporter | - |
BLL42_RS12580 | 2601643..2602098 | - | 456 | WP_071552384.1 | hypothetical protein | - |
BLL42_RS12585 | 2602343..2603308 | + | 966 | WP_071552385.1 | alpha/beta fold hydrolase | - |
BLL42_RS12590 | 2603346..2603762 | + | 417 | WP_071552386.1 | hypothetical protein | - |
BLL42_RS12595 | 2603769..2604221 | + | 453 | WP_071552387.1 | hypothetical protein | - |
BLL42_RS12600 | 2604412..2604642 | + | 231 | WP_054595147.1 | antitoxin | Antitoxin |
BLL42_RS12605 | 2604642..2605049 | + | 408 | WP_071552388.1 | tRNA(fMet)-specific endonuclease VapC | Toxin |
BLL42_RS12610 | 2605121..2606512 | - | 1392 | WP_071552389.1 | GABA permease | - |
BLL42_RS12615 | 2607067..2607840 | + | 774 | WP_071552390.1 | ABC transporter ATP-binding protein | - |
BLL42_RS12620 | 2607854..2608609 | + | 756 | WP_071552391.1 | ABC transporter substrate-binding protein | - |
BLL42_RS12625 | 2608690..2609385 | + | 696 | WP_071552392.1 | ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 136 a.a. Molecular weight: 15058.43 Da Isoelectric Point: 6.7508
>T68259 WP_071552388.1 NZ_CP017886:2604642-2605049 [Pseudomonas frederiksbergensis]
MIKYMLDTNICIFTIKNKPQVVRDAFNRHHGQLCISAVTLMELIYGAEKSAAPEKNLAVIEGFAARLEVLPFDYEAAAHT
GMIRSELAKAGTPIGPYDHMIAGHARSQGFIVVTNNLRELERVPGLRVEDWVHLD
MIKYMLDTNICIFTIKNKPQVVRDAFNRHHGQLCISAVTLMELIYGAEKSAAPEKNLAVIEGFAARLEVLPFDYEAAAHT
GMIRSELAKAGTPIGPYDHMIAGHARSQGFIVVTNNLRELERVPGLRVEDWVHLD
Download Length: 408 bp
>T68259 NZ_CP017886:2604642-2605049 [Pseudomonas frederiksbergensis]
ATGATCAAATACATGCTCGACACCAACATCTGCATTTTCACCATCAAGAACAAACCGCAGGTCGTGCGAGACGCGTTCAA
TCGCCATCACGGCCAGTTGTGCATCAGCGCAGTCACGCTGATGGAATTGATTTACGGCGCTGAAAAATCAGCGGCACCGG
AAAAGAACCTGGCCGTCATCGAGGGCTTTGCGGCTCGTCTTGAAGTCCTTCCCTTCGACTACGAAGCCGCTGCCCACACC
GGAATGATCCGCTCGGAACTTGCAAAAGCAGGAACACCAATAGGCCCTTACGATCACATGATTGCGGGTCACGCGCGCTC
ACAGGGGTTCATTGTGGTGACGAATAATCTTCGGGAGCTTGAGCGTGTTCCCGGATTGCGTGTAGAGGACTGGGTACACC
TCGATTGA
ATGATCAAATACATGCTCGACACCAACATCTGCATTTTCACCATCAAGAACAAACCGCAGGTCGTGCGAGACGCGTTCAA
TCGCCATCACGGCCAGTTGTGCATCAGCGCAGTCACGCTGATGGAATTGATTTACGGCGCTGAAAAATCAGCGGCACCGG
AAAAGAACCTGGCCGTCATCGAGGGCTTTGCGGCTCGTCTTGAAGTCCTTCCCTTCGACTACGAAGCCGCTGCCCACACC
GGAATGATCCGCTCGGAACTTGCAAAAGCAGGAACACCAATAGGCCCTTACGATCACATGATTGCGGGTCACGCGCGCTC
ACAGGGGTTCATTGTGGTGACGAATAATCTTCGGGAGCTTGAGCGTGTTCCCGGATTGCGTGTAGAGGACTGGGTACACC
TCGATTGA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8629.63 Da Isoelectric Point: 4.2683
>AT68259 WP_054595147.1 NZ_CP017886:2604412-2604642 [Pseudomonas frederiksbergensis]
MEQTTLFMSNRSQAVRLPKAVAMPEDVKRVNVVAIGRARIITPADEAWDSWFDGDNVTADFMADREQPADQERESF
MEQTTLFMSNRSQAVRLPKAVAMPEDVKRVNVVAIGRARIITPADEAWDSWFDGDNVTADFMADREQPADQERESF
Download Length: 231 bp
>AT68259 NZ_CP017886:2604412-2604642 [Pseudomonas frederiksbergensis]
ATGGAACAGACCACCCTTTTCATGAGTAATCGAAGCCAGGCTGTCCGCTTGCCCAAAGCAGTGGCAATGCCTGAAGACGT
GAAACGCGTCAATGTTGTAGCCATTGGTCGAGCTCGTATCATCACTCCGGCAGATGAAGCCTGGGATAGCTGGTTCGATG
GCGATAACGTCACTGCCGATTTCATGGCCGACCGTGAGCAACCGGCCGATCAGGAGCGCGAGTCGTTCTGA
ATGGAACAGACCACCCTTTTCATGAGTAATCGAAGCCAGGCTGTCCGCTTGCCCAAAGCAGTGGCAATGCCTGAAGACGT
GAAACGCGTCAATGTTGTAGCCATTGGTCGAGCTCGTATCATCACTCCGGCAGATGAAGCCTGGGATAGCTGGTTCGATG
GCGATAACGTCACTGCCGATTTCATGGCCGACCGTGAGCAACCGGCCGATCAGGAGCGCGAGTCGTTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1J0EK94 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1J0EKV4 |