Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3366141..3366286 Replicon chromosome
Accession NZ_CP017777
Organism Klebsiella pneumoniae strain KP36M

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3366148..3366250 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3366141..3366286 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BK002_RS15995 3361672..3363105 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BK002_RS16000 3363221..3363460 + 240 WP_002911393.1 YebV family protein -
BK002_RS16005 3363558..3363749 + 192 WP_002911395.1 YebW family protein -
BK002_RS16010 3363746..3364399 - 654 WP_024622748.1 protein-serine/threonine phosphatase -
BK002_RS16015 3364556..3365524 + 969 WP_014907334.1 VirK/YbjX family protein -
BK002_RS16020 3365629..3365772 + 144 WP_038431282.1 Ecr family regulatory small membrane protein -
- 3366141..3366286 + 146 - - Antitoxin
- 3366148..3366250 - 103 - - Toxin
BK002_RS16025 3366409..3366747 - 339 WP_002911404.1 YebY family protein -
BK002_RS16030 3366764..3367633 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
BK002_RS16035 3367637..3368011 - 375 WP_039819395.1 CopC domain-containing protein YobA -
BK002_RS16040 3368124..3368354 + 231 WP_002911406.1 DNA polymerase III subunit theta -
BK002_RS16045 3368433..3369092 + 660 WP_002911407.1 exodeoxyribonuclease X -
BK002_RS16050 3369096..3371156 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T68138 NZ_CP017777:c3366250-3366148 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT68138 NZ_CP017777:3366141-3366286 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References