Detailed information of TA system TA068125

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/PRK09907-MazE
• Location: 3458246..3458829
• Replicon: chromosome
• Accession: NZ_CP017762
• Organism: Virgibacillus sp. 6R

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: A0A0L0QLD2
• Locus tag: BKP57_RS15770
• Protein ID: WP_050351906.1
• Coordinates: 3458497..3458829 (+)
• Length: 111 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: -
• Locus tag: BKP57_RS15765
• Protein ID: WP_050353472.1
• Coordinates: 3458246..3458497 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (5-107)

Antitoxin

• SpoVT-AbrB domain (9-53)

Sequences

Toxin

Protein

• Length: 111 a.a.
• Molecular weight: 12084.97 Da
• Isoelectric Point: 6.9497

>T68125 WP_050351906.1 NZ_CP017762:3458497-3458829 [Virgibacillus sp. 6R]
MVAPERGDLVYVDFDAQSGREQAGIRPAIVLSPKQFNQITGFTVLCPITKTVRGWGYEVALPDSLAVSGVILTDKVKSVD
WNTRKLKIKGQAPEEIVEDCLAKIHTFLGQ

Nucleotide

• Length: 333 bp

>T68125 NZ_CP017762:3458497-3458829 [Virgibacillus sp. 6R]
ATGGTAGCACCAGAACGCGGCGATCTTGTATATGTGGATTTCGATGCGCAATCAGGACGTGAACAGGCTGGTATAAGACC
TGCGATTGTCCTATCCCCTAAACAATTCAATCAAATCACAGGATTTACTGTTCTGTGCCCAATTACAAAAACCGTCAGGG
GCTGGGGTTATGAAGTTGCGCTTCCTGACAGTTTAGCTGTGTCAGGAGTTATACTCACTGACAAAGTAAAAAGCGTAGAT
TGGAATACCAGAAAGTTAAAAATAAAAGGACAAGCTCCAGAAGAAATCGTTGAAGATTGCCTAGCTAAAATACATACATT
TTTAGGGCAATAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9296.61 Da
• Isoelectric Point: 5.6713

>AT68125 WP_050353472.1 NZ_CP017762:3458246-3458497 [Virgibacillus sp. 6R]
MTATATVSKWGNSLGVRIPKDMADSANINQGTEMTITLDQKGQIILTPIKNKKEYSLDELLNQCKPEHRHQEIDFGIKGE
ELI

Nucleotide

• Length: 252 bp

>AT68125 NZ_CP017762:3458246-3458497 [Virgibacillus sp. 6R]
ATGACTGCAACCGCTACTGTATCAAAATGGGGTAATAGTTTAGGGGTTAGAATTCCAAAAGACATGGCTGATTCAGCAAA
TATTAATCAAGGAACAGAAATGACAATTACTCTGGATCAAAAAGGACAAATCATTTTGACACCGATTAAGAATAAAAAAG
AATATTCCTTAGATGAATTATTAAATCAATGCAAACCAGAGCATCGTCATCAAGAAATTGATTTCGGAATAAAGGGGGAG
GAATTAATCTAA

Structures

Toxin

• AlphaFold DB: A0A0L0QLD2