Detailed information of TA system TA068123

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazF-pemI/MazF(toxin)
• Location: 1624265..1624913
• Replicon: chromosome
• Accession: NZ_CP017762
• Organism: Virgibacillus sp. 6R

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: A0A0L0QSJ8
• Locus tag: BKP57_RS07440
• Protein ID: WP_050351134.1
• Coordinates: 1624265..1624624 (-)
• Length: 120 a.a.

Antitoxin (Protein)

• Gene name: pemI
• Uniprot ID: -
• Locus tag: BKP57_RS07445
• Protein ID: WP_077298901.1
• Coordinates: 1624629..1624913 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (4-110)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 120 a.a.
• Molecular weight: 13455.69 Da
• Isoelectric Point: 8.4535

>T68123 WP_050351134.1 NZ_CP017762:c1624624-1624265 [Virgibacillus sp. 6R]
MIVQRGEVYFADLSPVVGSEQGGIRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKRYGFDRDSVILLEQI
RTLDKQRLTDKITKLDKEMMKKINQALEISLGLKDMYDQ

Nucleotide

• Length: 360 bp

>T68123 NZ_CP017762:c1624624-1624265 [Virgibacillus sp. 6R]
TTGATCGTACAAAGAGGCGAAGTGTATTTCGCTGACCTTTCCCCTGTTGTTGGATCAGAACAGGGAGGCATCCGCCCGGT
ATTGATCCTGCAAAATGATATCGGGAATCGTTTCAGTCCTACCGTTATTGTTGCTGCAATTACAGCGCAAATTCAAAAAG
CAAAGCTCCCTACTCATGTGGAGATTGATGCAAAACGATATGGGTTTGACCGTGATTCCGTTATTTTGCTAGAGCAAATA
CGAACACTTGATAAACAACGGTTAACAGATAAAATTACAAAATTAGATAAAGAAATGATGAAAAAGATCAACCAGGCATT
GGAAATCAGTTTAGGACTGAAGGATATGTATGATCAATGA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10867.21 Da
• Isoelectric Point: 4.5792

>AT68123 WP_077298901.1 NZ_CP017762:c1624913-1624629 [Virgibacillus sp. 6R]
MSESLQEVLVKIPKNLLNEVDGLVKYENSDLSDFICQATRNYLQHKRDEHFQQFRETMEKGYAEMGRINLTIASEAFQAE
EEAKNTLERSVIGV

Nucleotide

• Length: 285 bp

>AT68123 NZ_CP017762:c1624913-1624629 [Virgibacillus sp. 6R]
TTGTCAGAAAGCTTGCAAGAAGTATTAGTTAAAATACCGAAAAACCTGTTAAATGAGGTGGATGGTCTGGTGAAGTATGA
GAATAGTGATTTGAGTGATTTCATATGTCAGGCAACAAGGAACTATCTTCAGCATAAAAGAGATGAGCACTTTCAACAAT
TTCGCGAAACCATGGAAAAAGGTTATGCAGAAATGGGTCGTATTAATTTGACAATTGCTTCAGAAGCTTTTCAAGCTGAA
GAGGAAGCAAAAAACACCTTGGAACGCTCTGTGATCGGGGTGTAA

Structures

Toxin

• AlphaFold DB: A0A0L0QSJ8