Detailed information of TA system TA068083

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 71694..72319
• Replicon: plasmid pSARA13
• Accession: NZ_CP017729
• Organism: Salmonella enterica subsp. enterica serovar Typhimurium str. SARA13 strain SGSC 2193

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: SEETRA13_RS23735
• Protein ID: WP_000911322.1
• Coordinates: 71694..72092 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: SEETRA13_RS23740
• Protein ID: WP_000450265.1
• Coordinates: 72092..72319 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SEETRA13_RS23720	67885..68379	+	495	WP_010999946.1	entry exclusion protein	-
SEETRA13_RS23725	68415..69146	+	732	WP_000782438.1	complement resistance protein TraT	-
SEETRA13_RS23730	69523..71685	+	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
SEETRA13_RS23735	71694..72092	-	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
SEETRA13_RS23740	72092..72319	-	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..93826	93826

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Fido domain (13-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-50)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T68083 WP_000911322.1 NZ_CP017729:c72092-71694 [Salmonella enterica subsp. enterica serovar Typhimurium str. SARA13]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T68083 NZ_CP017729:c72092-71694 [Salmonella enterica subsp. enterica serovar Typhimurium str. SARA13]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT68083 WP_000450265.1 NZ_CP017729:c72319-72092 [Salmonella enterica subsp. enterica serovar Typhimurium str. SARA13]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 228 bp

>AT68083 NZ_CP017729:c72319-72092 [Salmonella enterica subsp. enterica serovar Typhimurium str. SARA13]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT