Detailed information of TA system TA068079

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 168946..169571
• Replicon: plasmid pCFSAN017963_01
• Accession: NZ_CP017721
• Organism: Salmonella enterica subsp. enterica serovar Minnesota strain CFSAN017963

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: A0A730EC68
• Locus tag: GX95_RS24995
• Protein ID: WP_071624913.1
• Coordinates: 168946..169344 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: GX95_RS25000
• Protein ID: WP_198385745.1
• Coordinates: 169344..169571 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GX95_RS24980	165212..165697	+	486	WP_088137264.1	surface exclusion protein	-
GX95_RS24985	165746..166477	+	732	WP_088137265.1	complement resistance protein TraT	-
GX95_RS24990	166730..168937	+	2208	WP_088137266.1	type IV conjugative transfer system coupling protein TraD	-
GX95_RS24995	168946..169344	-	399	WP_071624913.1	tRNA(fMet)-specific endonuclease VapC	Toxin
GX95_RS25000	169344..169571	-	228	WP_198385745.1	antitoxin	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..280421	280421

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (91-151)

Antitoxin

• Vibrio phage ICP1, Orf50 (8-86)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T68079 WP_071624913.1 NZ_CP017721:c169344-168946 [Salmonella enterica subsp. enterica serovar Minnesota]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T68079 NZ_CP017721:c169344-168946 [Salmonella enterica subsp. enterica serovar Minnesota]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT68079 WP_198385745.1 NZ_CP017721:c169571-169344 [Salmonella enterica subsp. enterica serovar Minnesota]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 228 bp

>AT68079 NZ_CP017721:c169571-169344 [Salmonella enterica subsp. enterica serovar Minnesota]
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Structures

Toxin

• AlphaFold DB: A0A730EC68