Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 1682385..1682887 Replicon chromosome
Accession NZ_CP017715
Organism Marinobacter salinus strain Hb8

Toxin (Protein)


Gene name yoeB Uniprot ID M7CQI7
Locus tag BKP64_RS07710 Protein ID WP_008938367.1
Coordinates 1682633..1682887 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID R8B220
Locus tag BKP64_RS07705 Protein ID WP_012137510.1
Coordinates 1682385..1682636 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BKP64_RS07680 1677520..1679091 - 1572 WP_070968112.1 transposase -
BKP64_RS07685 1679253..1679585 - 333 WP_070968133.1 hypothetical protein -
BKP64_RS07690 1679699..1680004 - 306 WP_198402661.1 hypothetical protein -
BKP64_RS07695 1680170..1681495 - 1326 WP_070973602.1 group II intron reverse transcriptase/maturase -
BKP64_RS07700 1682016..1682237 - 222 WP_070968138.1 hypothetical protein -
BKP64_RS07705 1682385..1682636 + 252 WP_012137510.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BKP64_RS07710 1682633..1682887 + 255 WP_008938367.1 Txe/YoeB family addiction module toxin Toxin
BKP64_RS07720 1683671..1684657 + 987 WP_070968145.1 integron integrase -
BKP64_RS07725 1684705..1685052 - 348 WP_070968148.1 4a-hydroxytetrahydrobiopterin dehydratase -
BKP64_RS07730 1685180..1685869 + 690 WP_070968151.1 translesion DNA synthesis-associated protein ImuA -
BKP64_RS07735 1685877..1687295 + 1419 WP_070968153.1 DNA polymerase Y family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1656095..1683320 27225


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10236.82 Da        Isoelectric Point: 9.8162

>T68074 WP_008938367.1 NZ_CP017715:1682633-1682887 [Marinobacter salinus]
MKLIFSENAWEDYLYWQKTDKKILNRINKLIKETKREPFEGVGKPEPLKHSLAGYWSRRINEEHRIVYKVTDDALLIAQL
RYHY

Download         Length: 255 bp

>T68074 NZ_CP017715:1682633-1682887 [Marinobacter salinus]
ATGAAACTCATCTTCTCTGAGAACGCCTGGGAAGACTATCTGTACTGGCAGAAAACCGACAAAAAGATTCTTAACCGAAT
CAACAAGCTGATTAAAGAGACCAAGCGAGAACCGTTCGAAGGTGTTGGCAAACCAGAGCCCCTCAAGCACAGCCTCGCAG
GGTACTGGTCTCGCCGAATCAACGAAGAACACCGAATAGTTTACAAAGTCACGGATGACGCTTTGCTTATCGCCCAACTC
CGGTATCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9269.50 Da        Isoelectric Point: 4.4750

>AT68074 WP_012137510.1 NZ_CP017715:1682385-1682636 [Marinobacter salinus]
MDAISYTAARTNLAKTMEQVCEDHSPVIITRSKSQSVVMISLEDYEALQETAYLLRAPKNARRLLESVAELEQGGGQEKE
LLE

Download         Length: 252 bp

>AT68074 NZ_CP017715:1682385-1682636 [Marinobacter salinus]
ATGGATGCCATCAGCTACACAGCCGCTAGAACCAATCTAGCAAAAACCATGGAGCAGGTCTGTGAAGACCATTCCCCTGT
GATCATTACCCGGAGCAAGTCCCAGTCAGTGGTTATGATCTCCTTGGAGGACTACGAGGCGCTGCAAGAAACGGCATACC
TTCTGCGCGCACCGAAAAACGCACGGCGTTTGCTGGAATCTGTTGCCGAACTAGAGCAAGGCGGTGGTCAAGAAAAGGAA
CTTCTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB M7CQI7

Antitoxin

Source ID Structure
AlphaFold DB A0A844I226

References