Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1476251..1476728 Replicon chromosome
Accession NZ_CP017708
Organism Moorea producens JHB

Toxin (Protein)


Gene name - Uniprot ID A0A1D9FVR4
Locus tag BJP36_RS05555 Protein ID WP_071102951.1
Coordinates 1476459..1476728 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1D9FVU8
Locus tag BJP36_RS05550 Protein ID WP_071102950.1
Coordinates 1476251..1476478 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJP36_RS05530 1471732..1473435 + 1704 WP_071102947.1 ABC-ATPase domain-containing protein -
BJP36_RS05535 1473491..1473914 + 424 Protein_1264 hypothetical protein -
BJP36_RS05540 1474109..1474969 + 861 WP_202970768.1 alpha/beta hydrolase -
BJP36_RS05545 1475201..1475569 + 369 WP_071102949.1 YccF domain-containing protein -
BJP36_RS05550 1476251..1476478 - 228 WP_071102950.1 CopG family transcriptional regulator Antitoxin
BJP36_RS05555 1476459..1476728 - 270 WP_071102951.1 BrnT family toxin Toxin
BJP36_RS05560 1476887..1479439 - 2553 WP_071107651.1 CHAT domain-containing protein -
BJP36_RS42510 1479717..1479863 + 147 WP_158026221.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin

CopG antitoxin

(5-69)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10525.90 Da        Isoelectric Point: 8.0069

>T68071 WP_071102951.1 NZ_CP017708:c1476728-1476459 [Moorena producens JHB]
VEFEFDDSKSQSNLAKHGINFKEAQQIWDNLDRVEIPARTEDEARFLVIGKIAQKCWSAIITYRENRVRIISVRRSRKEE
VAIYESNRI

Download         Length: 270 bp

>T68071 NZ_CP017708:c1476728-1476459 [Moorena producens JHB]
GTGGAATTTGAATTTGACGACTCTAAAAGCCAATCTAATTTAGCAAAGCACGGAATCAACTTCAAAGAGGCACAACAGAT
ATGGGACAATCTTGATCGAGTGGAAATCCCTGCTCGAACAGAAGACGAAGCGAGATTTCTTGTCATCGGTAAAATCGCTC
AAAAATGCTGGTCAGCCATCATTACCTATCGAGAAAACAGAGTACGGATTATCTCAGTCCGCCGATCGCGAAAAGAAGAG
GTAGCCATTTATGAAAGCAACAGAATTTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8776.99 Da        Isoelectric Point: 5.8580

>AT68071 WP_071102950.1 NZ_CP017708:c1476478-1476251 [Moorena producens JHB]
MKATEFDAKFDQGEDITEFLDLSRAKRPGHEQKRVNVDFPTWMIEALDREAKRLGVTRQSIIKVWLAERLEQLSS

Download         Length: 228 bp

>AT68071 NZ_CP017708:c1476478-1476251 [Moorena producens JHB]
ATGAAAGCAACAGAATTTGATGCCAAATTTGATCAGGGGGAAGACATTACTGAATTCTTAGACCTTTCCCGTGCCAAACG
TCCTGGACATGAGCAGAAACGAGTCAACGTTGATTTTCCAACTTGGATGATTGAAGCATTAGATCGCGAAGCCAAACGAT
TGGGGGTCACCCGTCAGTCAATTATTAAGGTATGGCTTGCGGAACGACTTGAACAGCTATCGTCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D9FVR4

Antitoxin

Source ID Structure
AlphaFold DB A0A1D9FVU8

References