Detailed information of TA system TA068067

Bioinformatically predicted

Overview

TA module

• Type: VII
• Classification (family/domain): HepT-MntA/HepT(toxin)
• Location: 3139430..3140300
• Replicon: chromosome
• Accession: NZ_CP017703
• Organism: Aeribacillus pallidus strain KCTC3564

Toxin (Protein)

• Gene name: hepT
• Uniprot ID: -
• Locus tag: AP3564_RS15590
• Protein ID: WP_094245918.1
• Coordinates: 3139827..3140300 (+)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: mntA
• Uniprot ID: -
• Locus tag: AP3564_RS15585
• Protein ID: WP_094245917.1
• Coordinates: 3139430..3139837 (+)
• Length: 136 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AP3564_RS15555	3134718..3135047	+	330	WP_094245912.1	hypothetical protein	-
AP3564_RS15560	3135374..3135993	-	620	Protein_2912	beta-lactamase family protein	-
AP3564_RS15565	3135975..3136598	-	624	WP_094245913.1	transposase	-
AP3564_RS15570	3136799..3137287	+	489	WP_157727979.1	hypothetical protein	-
AP3564_RS15575	3137393..3137812	+	420	WP_094245915.1	hypothetical protein	-
AP3564_RS15580	3137944..3139194	-	1251	WP_094245916.1	IS4 family transposase	-
AP3564_RS15585	3139430..3139837	+	408	WP_094245917.1	nucleotidyltransferase domain-containing protein	Antitoxin
AP3564_RS15590	3139827..3140300	+	474	WP_094245918.1	DUF86 domain-containing protein	Toxin
AP3564_RS15595	3140467..3140610	-	144	Protein_2919	PD-(D/E)XK nuclease family transposase	-
AP3564_RS15600	3140785..3144009	-	3225	WP_094245919.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	3112535..3278812	166277

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease HepT-like (14-131)

Antitoxin

• Polymerase beta, nucleotidyltransferase (9-99)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 18136.99 Da
• Isoelectric Point: 9.4892

>T68067 WP_094245918.1 NZ_CP017703:3139827-3140300 [Aeribacillus pallidus]
MKNDVILNKISVIERCIKRIHEEYENNPKNLENYTKQDSIILNLQRACEASIDLAMHMVAQKKLGLPQNSRDAFSLLEQH
GIITPFLSQKMKAMVGFRNIAVHDYQEINLTILQKILDHHLTDFTEFTKAIFFMSSKAGGADAHRPSMLFKQRHNSR

Nucleotide

• Length: 474 bp

>T68067 NZ_CP017703:3139827-3140300 [Aeribacillus pallidus]
ATGAAAAATGATGTCATTTTAAATAAAATTAGCGTGATCGAGCGGTGCATAAAGCGCATTCACGAAGAATATGAGAACAA
CCCGAAAAATTTAGAAAACTACACGAAGCAAGACTCCATTATCTTAAATCTCCAACGAGCATGTGAAGCAAGCATCGACT
TGGCGATGCACATGGTCGCACAGAAAAAGCTAGGCCTCCCCCAAAACAGTCGAGACGCTTTTTCTCTTTTAGAACAGCAC
GGCATCATCACTCCTTTTCTTTCACAAAAAATGAAAGCGATGGTCGGATTTAGAAACATCGCCGTTCACGACTACCAGGA
AATTAATTTGACCATTTTGCAAAAAATACTTGATCACCATCTAACCGACTTTACCGAGTTCACGAAAGCGATTTTTTTTA
TGAGCAGTAAAGCGGGCGGTGCAGATGCGCACCGTCCGAGCATGTTATTTAAGCAAAGACATAATTCAAGATAG

Antitoxin

Protein

• Length: 136 a.a.
• Molecular weight: 15597.65 Da
• Isoelectric Point: 4.6889

>AT68067 WP_094245917.1 NZ_CP017703:3139430-3139837 [Aeribacillus pallidus]
MTEQIEPIIIEVLTETVSPYLIYLFGSTVAGHVHQDSDIDIAFLSDQKQLDHYERFMVAQELASRLHRDVDLVDLKQAST
VFQAQVVSNGKVIYCTNEQKKAEYEWRALKMYAKLNEERAEILRNINESGSVYEK

Nucleotide

• Length: 408 bp

>AT68067 NZ_CP017703:3139430-3139837 [Aeribacillus pallidus]
TTGACTGAACAGATCGAGCCAATCATTATTGAAGTGTTGACAGAAACGGTGTCCCCATATTTGATTTATTTGTTTGGATC
AACGGTTGCAGGACATGTTCATCAAGACAGCGACATTGATATCGCTTTTCTCAGCGACCAAAAACAATTGGATCATTATG
AACGATTTATGGTTGCGCAAGAATTGGCATCCAGGCTGCACCGGGATGTCGATCTTGTGGACCTCAAACAAGCAAGCACC
GTGTTTCAGGCGCAAGTGGTCAGTAACGGCAAAGTCATCTATTGTACAAATGAACAGAAAAAAGCCGAATATGAATGGAG
AGCCTTGAAGATGTATGCAAAATTGAATGAAGAACGCGCGGAAATCTTGCGAAACATTAATGAAAGCGGGTCGGTTTATG
AAAAATGA