Detailed information of TA system TA068059

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1500548..1501073
• Replicon: chromosome
• Accession: NZ_CP017689
• Organism: Thalassotalea crassostreae strain LPB0090

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LT090_RS06535
• Protein ID: WP_068545136.1
• Coordinates: 1500548..1500835 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LT090_RS06540
• Protein ID: WP_068545137.1
• Coordinates: 1500825..1501073 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LT090_RS06490	1496575..1497171	+	597	WP_068545133.1	dCTP deaminase	-
LT090_RS06495	1497284..1498216	-	933	WP_068545134.1	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	-
LT090_RS06525	1499648..1500187	-	540	WP_082897059.1	hypothetical protein	-
LT090_RS06535	1500548..1500835	-	288	WP_068545136.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LT090_RS06540	1500825..1501073	-	249	WP_068545137.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
LT090_RS06545	1501265..1502167	+	903	WP_157726592.1	TatD family hydrolase	-
LT090_RS06550	1502181..1502513	+	333	WP_089152985.1	MipA/OmpV family protein	-
LT090_RS06555	1502719..1504818	+	2100	WP_068545139.1	hypothetical protein	-
LT090_RS06560	1504863..1505363	-	501	WP_068545140.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-72)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11054.93 Da
• Isoelectric Point: 10.5708

>T68059 WP_068545136.1 NZ_CP017689:c1500835-1500548 [Thalassotalea crassostreae]
MTYKLEFKKSALKEWKKLGATLQAQFKKKLIERLSNPHVQPDKLSGAENLYKIKLRQAGYRLVYEVEDNVVTITVLAVGK
RERGNVYDQAFKRLN

Nucleotide

• Length: 288 bp

>T68059 NZ_CP017689:c1500835-1500548 [Thalassotalea crassostreae]
ATGACTTATAAGCTTGAATTTAAAAAATCAGCTTTGAAGGAGTGGAAAAAATTAGGTGCCACACTTCAAGCTCAGTTTAA
AAAGAAGCTAATTGAACGTCTATCCAATCCTCATGTTCAGCCTGATAAACTATCTGGGGCAGAAAATTTATACAAAATTA
AGCTTCGCCAAGCAGGATATCGGTTAGTTTATGAAGTTGAAGACAATGTGGTGACTATTACAGTGCTAGCTGTTGGCAAA
AGAGAGCGTGGAAATGTTTATGATCAAGCATTCAAGAGACTAAATTAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9070.50 Da
• Isoelectric Point: 4.3085

>AT68059 WP_068545137.1 NZ_CP017689:c1501073-1500825 [Thalassotalea crassostreae]
MTTRILTEIAASITELKSNPMKVVSSAHGDPIAVLNRNEPAFYCIPAKAYELLMEKLEDLELLALVDERKNEPSIAVSID
DL

Nucleotide

• Length: 249 bp

>AT68059 NZ_CP017689:c1501073-1500825 [Thalassotalea crassostreae]
ATGACTACCCGCATATTAACAGAAATAGCAGCAAGTATTACAGAATTAAAATCTAACCCTATGAAAGTCGTGTCTAGTGC
ACACGGTGACCCTATTGCCGTGCTAAATAGGAATGAACCAGCTTTCTATTGTATCCCAGCAAAAGCCTATGAGCTATTAA
TGGAAAAACTTGAAGATCTAGAGCTACTAGCTTTAGTAGATGAACGTAAAAATGAACCTTCAATAGCGGTTAGCATTGAT
GACTTATAA