Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1323357..1324123 Replicon chromosome
Accession NZ_CP017689
Organism Thalassotalea crassostreae strain LPB0090

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag LT090_RS05730 Protein ID WP_068546552.1
Coordinates 1323626..1324123 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag LT090_RS05725 Protein ID WP_068546551.1
Coordinates 1323357..1323623 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT090_RS05705 1319852..1320937 + 1086 WP_157726629.1 hypothetical protein -
LT090_RS05710 1320930..1321400 + 471 WP_068546548.1 hypothetical protein -
LT090_RS05715 1321647..1322321 + 675 WP_068546549.1 hypothetical protein -
LT090_RS05720 1322484..1323065 - 582 WP_068546550.1 DUF1523 family protein -
LT090_RS05725 1323357..1323623 + 267 WP_068546551.1 DUF1778 domain-containing protein Antitoxin
LT090_RS05730 1323626..1324123 + 498 WP_068546552.1 GNAT family N-acetyltransferase Toxin
LT090_RS05735 1324298..1324840 + 543 WP_068546553.1 hypothetical protein -
LT090_RS05740 1325132..1325881 + 750 WP_068546554.1 HNH endonuclease family protein -
LT090_RS05745 1325938..1327875 - 1938 WP_068546555.1 hypothetical protein -
LT090_RS05750 1328156..1328704 - 549 WP_068546556.1 SPOR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(29-145)

Antitoxin

Vibrio phage ICP1, Orf50

(7-81)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18352.34 Da        Isoelectric Point: 9.8842

>T68058 WP_068546552.1 NZ_CP017689:1323626-1324123 [Thalassotalea crassostreae]
MQLCVPVALNHKHNCCNFDCENDTLNQWLYKRALKNQQSGASKTFVTCLGDNVAGFYSLSTGSIEHKYVSAALKRNMPAP
IPIIILSRLAVDHSFKGKGLGKHLLKDALLRILQVSQNIGVRAVVVHAINQDVIEFYKQFGFQQSPLTSHTLYLSVRSIK
LALSN

Download         Length: 498 bp

>T68058 NZ_CP017689:1323626-1324123 [Thalassotalea crassostreae]
ATGCAACTTTGTGTTCCTGTTGCATTAAATCATAAGCACAACTGCTGCAATTTTGATTGCGAAAACGATACGTTAAATCA
GTGGCTTTACAAACGGGCTCTTAAAAACCAACAAAGTGGCGCTTCAAAAACCTTCGTAACTTGTTTAGGCGATAACGTTG
CAGGTTTCTATTCTTTATCAACTGGCAGTATTGAACATAAATACGTATCAGCAGCACTTAAACGTAATATGCCAGCCCCA
ATCCCAATTATCATTTTATCTAGGCTTGCGGTAGATCATTCTTTTAAGGGAAAAGGACTTGGTAAGCACCTGTTAAAAGA
TGCGTTACTTAGAATATTGCAGGTGTCACAAAACATCGGGGTAAGAGCTGTTGTGGTACACGCTATCAATCAAGACGTAA
TCGAGTTTTATAAACAGTTTGGATTTCAACAATCACCGTTAACATCACACACGTTATACCTATCCGTTAGATCGATTAAA
TTAGCTCTATCAAATTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9994.47 Da        Isoelectric Point: 4.7954

>AT68058 WP_068546551.1 NZ_CP017689:1323357-1323623 [Thalassotalea crassostreae]
MAKTAPINMRVEPAQQDLLTKAAAALNMDRSTFILNVACKEAENVLLDQRIFNLDEEQFAQFEQAINEPVAHYKLSKLMS
EKSPWEAK

Download         Length: 267 bp

>AT68058 NZ_CP017689:1323357-1323623 [Thalassotalea crassostreae]
ATGGCTAAGACAGCCCCAATAAATATGCGTGTTGAGCCGGCGCAGCAAGATTTATTAACGAAAGCTGCTGCGGCTTTAAA
TATGGATCGCAGCACGTTTATACTTAATGTTGCATGCAAAGAAGCAGAGAATGTATTGCTCGATCAGCGGATTTTTAATT
TAGATGAAGAGCAATTTGCTCAATTTGAGCAAGCGATAAATGAACCCGTTGCACATTATAAGTTAAGCAAGTTAATGTCA
GAAAAATCCCCATGGGAAGCAAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References