67970

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3229912..3230569 Replicon chromosome
Accession NZ_CP017671
Organism Providencia rettgeri strain RB151

Toxin (Protein)


Gene name cptA Uniprot ID A0A1J0E9L4
Locus tag RB151_RS14890 Protein ID WP_042845040.1
Coordinates 3229912..3230322 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1J0E9J6
Locus tag RB151_RS14895 Protein ID WP_042845042.1
Coordinates 3230303..3230569 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RB151_RS14870 3225851..3227584 - 1734 WP_042845035.1 single-stranded-DNA-specific exonuclease RecJ -
RB151_RS14875 3227594..3228298 - 705 WP_071548860.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
RB151_RS14880 3228320..3229222 - 903 WP_042845037.1 site-specific tyrosine recombinase XerD -
RB151_RS14885 3229340..3229858 + 519 WP_042845038.1 flavodoxin FldB -
RB151_RS14890 3229912..3230322 - 411 WP_042845040.1 protein YgfX Toxin
RB151_RS14895 3230303..3230569 - 267 WP_042845042.1 FAD assembly factor SdhE Antitoxin
RB151_RS14900 3230819..3231808 + 990 WP_071548273.1 tRNA-modifying protein YgfZ -
RB151_RS14905 3231820..3232440 + 621 WP_071548274.1 HD domain-containing protein -
RB151_RS14910 3232595..3233491 + 897 WP_048607912.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15461.25 Da        Isoelectric Point: 10.6538

>T67970 WP_042845040.1 NZ_CP017671:c3230322-3229912 [Providencia rettgeri]
VVLWKSNLSISWKTQFFSTCVHGAVGMFLLVAPWAPAHSMIWLPLLAVVVASWAKSQKNISKIKGVAVLVNGNKVQWKKN
EWNIVKAPWLSRYGILLSLEALQGKQQKIHLWVAKDSVSEESWRNLNQLLLQYPDI

Download         Length: 411 bp

>T67970 NZ_CP017671:c3230322-3229912 [Providencia rettgeri]
GTGGTCCTGTGGAAATCTAATCTTTCCATTTCATGGAAAACACAGTTTTTTTCAACCTGTGTTCATGGGGCAGTAGGCAT
GTTTTTGCTTGTTGCACCATGGGCACCGGCTCATTCAATGATATGGTTGCCACTTCTTGCGGTTGTGGTGGCTAGTTGGG
CAAAAAGCCAAAAGAACATCAGCAAAATAAAAGGGGTTGCTGTGTTGGTTAATGGTAATAAAGTCCAATGGAAAAAGAAT
GAATGGAATATTGTGAAAGCACCTTGGTTGAGCCGCTATGGCATCTTATTGTCATTAGAAGCTTTACAAGGTAAGCAACA
AAAAATTCACCTATGGGTTGCTAAAGACTCTGTTTCTGAGGAAAGTTGGCGTAATTTGAACCAATTATTACTTCAATACC
CTGATATTTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10619.16 Da        Isoelectric Point: 4.8780

>AT67970 WP_042845042.1 NZ_CP017671:c3230569-3230303 [Providencia rettgeri]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDSLTTNDKQVFVRLLECADPDLFNWLMNHGRPDDDELFRMVKLIQEKN
KNRGPVEI

Download         Length: 267 bp

>AT67970 NZ_CP017671:c3230569-3230303 [Providencia rettgeri]
ATGGATATTGAGAACAAGGCGCGAATTCATTGGGCTTGTCGCCGCGGTATGCGTGAGCTAGATATTTCAATCATGCCATT
TTTTGAGTATGAATATGATAGTCTGACAACCAATGATAAACAGGTGTTTGTCCGTTTATTGGAGTGTGCGGACCCTGATT
TATTTAACTGGTTAATGAATCACGGTCGCCCAGATGACGACGAGCTATTTCGTATGGTAAAACTGATTCAGGAAAAAAAT
AAAAATCGTGGTCCTGTGGAAATCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J0E9L4

Antitoxin

Source ID Structure
AlphaFold DB A0A1J0E9J6

References