Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/DinJ(antitoxin)
Location 1859493..1860108 Replicon chromosome
Accession NZ_CP017666
Organism Streptococcus suis strain 0061

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BKM66_RS08975 Protein ID WP_161496224.1
Coordinates 1859493..1859828 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag BKM66_RS08980 Protein ID WP_105183605.1
Coordinates 1859821..1860108 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BKM66_RS08950 1854714..1856057 - 1344 WP_105183602.1 cysteine--tRNA ligase -
BKM66_RS08955 1856068..1856253 - 186 WP_105183603.1 hypothetical protein -
BKM66_RS08960 1856351..1856968 - 618 WP_024400199.1 serine O-acetyltransferase -
BKM66_RS08965 1857022..1859241 - 2220 WP_105183604.1 polyribonucleotide nucleotidyltransferase -
BKM66_RS08975 1859493..1859828 - 336 WP_161496224.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BKM66_RS08980 1859821..1860108 - 288 WP_105183605.1 hypothetical protein Antitoxin
BKM66_RS08985 1860527..1860796 - 270 WP_002938849.1 30S ribosomal protein S15 -
BKM66_RS08990 1860999..1862276 - 1278 WP_024393459.1 NCS2 family nucleobase:cation symporter -
BKM66_RS08995 1862530..1864425 - 1896 WP_044673271.1 DUF262 domain-containing HNH endonuclease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-96)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12783.86 Da        Isoelectric Point: 9.5189

>T67929 WP_161496224.1 NZ_CP017666:c1859828-1859493 [Streptococcus suis]
MDKYQVNLPLAIYEELAAIRSYIREELKSPDAADKKIQELIAGLRSLEIFPERGFNVDERSKKGPLVPGHLTRGLPIKKD
YIAIYNIDEAQKVVNVRYLVASKSDYMRLFK

Download         Length: 336 bp

>T67929 NZ_CP017666:c1859828-1859493 [Streptococcus suis]
TTGGATAAGTACCAAGTAAACCTACCTCTAGCTATATATGAGGAACTAGCTGCCATTCGTAGCTACATCAGGGAAGAACT
AAAAAGTCCTGATGCTGCGGACAAAAAAATCCAAGAGCTAATAGCAGGACTTAGAAGCCTTGAAATCTTCCCAGAGCGAG
GTTTTAACGTAGATGAACGCTCTAAAAAAGGACCGCTAGTCCCAGGTCACCTGACGCGAGGACTACCCATCAAAAAGGAT
TATATAGCTATTTATAACATTGATGAAGCACAAAAGGTCGTAAACGTTCGCTATCTTGTCGCAAGCAAGAGCGACTATAT
GAGATTGTTCAAATAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10714.39 Da        Isoelectric Point: 4.2626

>AT67929 WP_105183605.1 NZ_CP017666:c1860108-1859821 [Streptococcus suis]
MALTAEKKLINFQSEKSLVEEAKEVLASQNMTMTQALNLFLKNIVVTGEIGLKSEEELEKERLFVELQAEVMKNVAEMNA
GNYLSLDEMETKLFG

Download         Length: 288 bp

>AT67929 NZ_CP017666:c1860108-1859821 [Streptococcus suis]
ATGGCCTTAACAGCTGAAAAGAAATTGATTAACTTTCAATCAGAGAAATCACTTGTAGAAGAAGCAAAAGAGGTCTTGGC
AAGTCAAAATATGACCATGACACAAGCTCTCAACCTGTTTCTCAAAAATATTGTAGTAACAGGAGAAATTGGGCTTAAAA
GTGAAGAAGAACTGGAAAAAGAGCGACTATTTGTCGAACTGCAAGCAGAAGTGATGAAAAATGTAGCTGAAATGAATGCG
GGCAACTATCTATCATTGGACGAAATGGAGACCAAGCTCTTTGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References