Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-YefM
Location 3719424..3719971 Replicon chromosome
Accession NZ_CP017660
Organism Cellulosimicrobium sp. JZ28

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BJP59_RS16645 Protein ID WP_021483657.1
Coordinates 3719693..3719971 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BJP59_RS16640 Protein ID WP_021483656.1
Coordinates 3719424..3719696 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJP59_RS16615 3714897..3715538 - 642 WP_163185196.1 hypothetical protein -
BJP59_RS16620 3715774..3718071 + 2298 WP_194521492.1 carbon starvation protein A -
BJP59_RS16625 3718197..3718334 + 138 WP_081599979.1 YbdD/YjiX family protein -
BJP59_RS16630 3718353..3718814 + 462 WP_194521493.1 hypothetical protein -
BJP59_RS16635 3718820..3719338 + 519 WP_194521494.1 hypothetical protein -
BJP59_RS16640 3719424..3719696 + 273 WP_021483656.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BJP59_RS16645 3719693..3719971 + 279 WP_021483657.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BJP59_RS16650 3719994..3720464 - 471 WP_194521495.1 META domain-containing protein -
BJP59_RS16655 3720555..3721175 + 621 WP_021482172.1 hypothetical protein -
BJP59_RS16660 3721153..3722079 - 927 WP_194521496.1 siderophore-interacting protein -
BJP59_RS16665 3722066..3723049 - 984 WP_194521497.1 iron-siderophore ABC transporter substrate-binding protein -
BJP59_RS16670 3723118..3724290 + 1173 WP_194521498.1 histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-71)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10251.79 Da        Isoelectric Point: 8.9088

>T67912 WP_021483657.1 NZ_CP017660:3719693-3719971 [Cellulosimicrobium sp. JZ28]
VTDVDGGWEVRLSPPAARTLYQLPPRLADAVIRFCDEPLASNPYRVTKALGAELAGQRAGYVGIGFRVLVRIDDDQRLVT
VMRMAYRADAYR

Download         Length: 279 bp

>T67912 NZ_CP017660:3719693-3719971 [Cellulosimicrobium sp. JZ28]
GTGACCGACGTCGACGGTGGGTGGGAGGTGCGCCTGAGCCCACCGGCCGCACGCACGCTCTACCAGCTCCCCCCACGCCT
GGCCGACGCCGTGATCCGCTTCTGCGACGAACCACTCGCGTCGAACCCCTACCGGGTGACGAAGGCGCTCGGGGCCGAGC
TCGCCGGCCAGCGTGCCGGGTACGTCGGGATCGGGTTCCGCGTCCTGGTCCGCATCGACGACGACCAGCGTCTGGTCACC
GTGATGCGGATGGCCTACCGCGCCGACGCCTACCGGTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9734.91 Da        Isoelectric Point: 4.5008

>AT67912 WP_021483656.1 NZ_CP017660:3719424-3719696 [Cellulosimicrobium sp. JZ28]
VHTYPMSEAKTNLSALVDEVESTHQPVTITRHGKAAAVLIAPEDLATLMETLAWLSDPDHGAEMAEAEEAVAQGRTLSLA
EVREQLASRR

Download         Length: 273 bp

>AT67912 NZ_CP017660:3719424-3719696 [Cellulosimicrobium sp. JZ28]
GTGCACACCTATCCCATGAGCGAAGCGAAGACCAACCTGTCCGCCCTGGTCGACGAGGTGGAGAGCACCCACCAACCGGT
GACGATCACCCGTCACGGGAAGGCGGCGGCGGTGCTGATCGCGCCGGAAGACCTGGCGACGCTCATGGAGACGCTGGCAT
GGCTGTCCGACCCTGACCACGGGGCCGAGATGGCCGAGGCCGAGGAGGCGGTGGCGCAGGGCCGCACCCTGAGCCTCGCC
GAGGTGCGCGAGCAGCTGGCCTCGCGACGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References