Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 2266827..2267422 Replicon chromosome
Accession NZ_CP017638
Organism Dickeya dianthicola RNS04.9

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag DDI_RS10535 Protein ID WP_024106154.1
Coordinates 2266827..2267204 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag DDI_RS10540 Protein ID WP_024106155.1
Coordinates 2267201..2267422 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DDI_RS10510 2262659..2263282 - 624 WP_024106150.1 glutathione S-transferase family protein -
DDI_RS10515 2263623..2263771 - 149 Protein_2036 transposase -
DDI_RS10520 2263882..2265438 - 1557 WP_024106152.1 HD domain-containing protein -
DDI_RS10525 2265766..2266272 - 507 WP_024106153.1 hypothetical protein -
DDI_RS10535 2266827..2267204 - 378 WP_024106154.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
DDI_RS10540 2267201..2267422 - 222 WP_024106155.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
DDI_RS10545 2267558..2268706 - 1149 WP_024106156.1 L-threonine dehydrogenase -
DDI_RS10550 2268987..2269547 + 561 WP_026594941.1 NUDIX domain-containing protein -
DDI_RS10555 2269619..2270296 - 678 WP_024106158.1 respiratory nitrate reductase subunit gamma -
DDI_RS10560 2270296..2271015 - 720 WP_024106159.1 nitrate reductase molybdenum cofactor assembly chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14239.25 Da        Isoelectric Point: 5.1873

>T67885 WP_024106154.1 NZ_CP017638:c2267204-2266827 [Dickeya dianthicola RNS04.9]
MKWVSAQDVIAFHDRILQVLPGVAGMADPSRAEALIYRVQNRLYYEDMTDLFELAATYWVTVARGHIFNDGNKRTAFFVT
MVFLRRNGVLIADNDNSLEELTVKAATGECQVSELAEQLRQRVEK

Download         Length: 378 bp

>T67885 NZ_CP017638:c2267204-2266827 [Dickeya dianthicola RNS04.9]
ATGAAATGGGTCAGTGCGCAGGACGTTATCGCCTTTCATGATCGCATCCTGCAGGTGTTGCCAGGAGTTGCTGGTATGGC
GGATCCTAGCCGGGCTGAAGCCTTGATTTATCGGGTGCAGAACCGGCTTTATTATGAAGATATGACGGATCTCTTTGAAC
TGGCAGCGACGTATTGGGTAACTGTTGCGCGGGGTCATATTTTTAATGATGGTAATAAGCGCACCGCTTTTTTCGTCACC
ATGGTATTTTTACGCCGCAATGGCGTATTAATTGCCGATAACGACAATTCATTGGAAGAGCTTACCGTCAAGGCAGCAAC
GGGTGAATGTCAGGTGTCGGAACTCGCGGAGCAGTTAAGACAGCGTGTGGAAAAGTAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8121.15 Da        Isoelectric Point: 6.4602

>AT67885 WP_024106155.1 NZ_CP017638:c2267422-2267201 [Dickeya dianthicola RNS04.9]
MKTYTITEARQNIAAVIDTAASGEPVEITRRNGTSAVLIPKAEFEAYQNARLDAEFDFIMQRHGHTVKALADR

Download         Length: 222 bp

>AT67885 NZ_CP017638:c2267422-2267201 [Dickeya dianthicola RNS04.9]
ATGAAAACGTACACCATTACTGAAGCCCGGCAAAACATTGCGGCGGTCATCGATACGGCGGCCAGCGGCGAGCCGGTGGA
AATTACGCGTCGAAATGGTACGTCGGCCGTACTCATCCCTAAGGCGGAGTTTGAGGCTTATCAGAACGCCAGACTAGACG
CTGAATTTGATTTCATCATGCAGCGCCACGGCCACACGGTTAAAGCGCTTGCCGACAGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References