Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 1988483..1989393 | Replicon | chromosome |
| Accession | NZ_CP017638 | ||
| Organism | Dickeya dianthicola RNS04.9 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | DDI_RS09350 | Protein ID | WP_024105930.1 |
| Coordinates | 1988923..1989393 (+) | Length | 157 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A3A4C852 |
| Locus tag | DDI_RS09345 | Protein ID | WP_024105929.1 |
| Coordinates | 1988483..1988926 (+) | Length | 148 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DDI_RS09320 | 1983541..1984212 | + | 672 | WP_024105924.1 | dethiobiotin synthase | - |
| DDI_RS09325 | 1984486..1984842 | - | 357 | WP_024105925.1 | DUF1283 family protein | - |
| DDI_RS09330 | 1985048..1985797 | - | 750 | WP_024105926.1 | bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG | - |
| DDI_RS09335 | 1986101..1987327 | - | 1227 | WP_024105927.1 | glycosyl transferase | - |
| DDI_RS09340 | 1987346..1988173 | - | 828 | WP_024105928.1 | mannosyl-3-phosphoglycerate phosphatase-related protein | - |
| DDI_RS09345 | 1988483..1988926 | + | 444 | WP_024105929.1 | DUF2384 domain-containing protein | Antitoxin |
| DDI_RS09350 | 1988923..1989393 | + | 471 | WP_024105930.1 | RES family NAD+ phosphorylase | Toxin |
| DDI_RS21900 | 1989399..1989686 | + | 288 | WP_024105931.1 | hypothetical protein | - |
| DDI_RS21905 | 1989763..1990035 | - | 273 | WP_187299600.1 | hypothetical protein | - |
| DDI_RS09360 | 1990103..1991107 | - | 1005 | WP_024105933.1 | acyltransferase family protein | - |
| DDI_RS09370 | 1991799..1992760 | + | 962 | Protein_1805 | dicarboxylate transporter/tellurite-resistance protein TehA | - |
| DDI_RS09375 | 1993061..1993759 | + | 699 | WP_081634336.1 | Expansin-YoaJ | - |
| DDI_RS09385 | 1994000..1994295 | - | 296 | Protein_1807 | TetR/AcrR family transcriptional regulator C-terminal domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 157 a.a. Molecular weight: 17578.95 Da Isoelectric Point: 4.7269
>T67884 WP_024105930.1 NZ_CP017638:1988923-1989393 [Dickeya dianthicola RNS04.9]
MILYRLTKTKYLSTVWTGYGAKEAGGRWNSVGVSMVYVSETASLTMLETLVHLHAAHILDYYTLLRIDVPDDHIQSVNMN
DLPENWAEEDAPPELAAYGDAWCFTKSSIALRVPSTLSPVEFNYLLNPEHPDFSSIIQNADTIPFQFDSRLKPAIK
MILYRLTKTKYLSTVWTGYGAKEAGGRWNSVGVSMVYVSETASLTMLETLVHLHAAHILDYYTLLRIDVPDDHIQSVNMN
DLPENWAEEDAPPELAAYGDAWCFTKSSIALRVPSTLSPVEFNYLLNPEHPDFSSIIQNADTIPFQFDSRLKPAIK
Download Length: 471 bp
>T67884 NZ_CP017638:1988923-1989393 [Dickeya dianthicola RNS04.9]
TTGATTCTCTACAGGCTGACCAAGACAAAATATCTTTCTACAGTCTGGACGGGATATGGGGCAAAAGAGGCAGGAGGTCG
CTGGAACAGTGTAGGTGTCTCGATGGTATATGTGTCTGAAACAGCATCGCTTACGATGCTTGAGACGCTTGTACATCTGC
ATGCTGCACATATTCTGGATTATTATACTCTGCTGCGTATTGATGTCCCTGATGACCATATTCAGAGCGTCAATATGAAC
GACTTGCCAGAAAATTGGGCTGAAGAAGACGCGCCGCCTGAGCTTGCTGCTTACGGTGATGCTTGGTGCTTTACCAAAAG
TTCGATAGCCTTGCGTGTCCCCAGCACTTTATCTCCCGTGGAATTTAACTACCTTTTAAACCCCGAGCACCCTGACTTCT
CCTCGATCATCCAGAACGCTGACACCATTCCGTTCCAGTTTGATAGCAGGCTGAAACCGGCGATTAAATAG
TTGATTCTCTACAGGCTGACCAAGACAAAATATCTTTCTACAGTCTGGACGGGATATGGGGCAAAAGAGGCAGGAGGTCG
CTGGAACAGTGTAGGTGTCTCGATGGTATATGTGTCTGAAACAGCATCGCTTACGATGCTTGAGACGCTTGTACATCTGC
ATGCTGCACATATTCTGGATTATTATACTCTGCTGCGTATTGATGTCCCTGATGACCATATTCAGAGCGTCAATATGAAC
GACTTGCCAGAAAATTGGGCTGAAGAAGACGCGCCGCCTGAGCTTGCTGCTTACGGTGATGCTTGGTGCTTTACCAAAAG
TTCGATAGCCTTGCGTGTCCCCAGCACTTTATCTCCCGTGGAATTTAACTACCTTTTAAACCCCGAGCACCCTGACTTCT
CCTCGATCATCCAGAACGCTGACACCATTCCGTTCCAGTTTGATAGCAGGCTGAAACCGGCGATTAAATAG
Antitoxin
Download Length: 148 a.a. Molecular weight: 16506.81 Da Isoelectric Point: 9.6195
>AT67884 WP_024105929.1 NZ_CP017638:1988483-1988926 [Dickeya dianthicola RNS04.9]
MKTFSLSTTQTRPPRLWQVAGLNNSDGVALLGQINEGLDGTVANVIIDWAKITQNDLRKMSGIPSTTFSRSRKARFTADQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKVPAELMASETGAYEVMKLITRLEHGAYS
MKTFSLSTTQTRPPRLWQVAGLNNSDGVALLGQINEGLDGTVANVIIDWAKITQNDLRKMSGIPSTTFSRSRKARFTADQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKVPAELMASETGAYEVMKLITRLEHGAYS
Download Length: 444 bp
>AT67884 NZ_CP017638:1988483-1988926 [Dickeya dianthicola RNS04.9]
ATGAAAACATTTAGCTTATCCACGACACAGACCCGGCCGCCACGCTTGTGGCAGGTTGCGGGGTTAAACAATTCTGATGG
TGTAGCACTGCTGGGCCAGATTAACGAAGGCCTTGATGGCACAGTTGCAAACGTGATCATTGACTGGGCAAAGATCACGC
AGAACGACCTGCGCAAAATGTCCGGTATACCGTCCACGACATTCAGTCGTAGCCGGAAAGCCCGATTCACCGCCGACCAA
AGTGAGCGACTGGTGCGCATTATTCGCGTTATAGATCGGGCTGTAGAACTGTTCGAGGGTGATAAAGACGAGGCCCAGAA
ATGGTTGAATGAGCCAAACAGAGCACTGAGCTGGAAAGTGCCAGCGGAACTGATGGCCTCCGAAACCGGCGCTTACGAGG
TCATGAAATTGATTACACGCCTGGAGCATGGGGCATACTCTTGA
ATGAAAACATTTAGCTTATCCACGACACAGACCCGGCCGCCACGCTTGTGGCAGGTTGCGGGGTTAAACAATTCTGATGG
TGTAGCACTGCTGGGCCAGATTAACGAAGGCCTTGATGGCACAGTTGCAAACGTGATCATTGACTGGGCAAAGATCACGC
AGAACGACCTGCGCAAAATGTCCGGTATACCGTCCACGACATTCAGTCGTAGCCGGAAAGCCCGATTCACCGCCGACCAA
AGTGAGCGACTGGTGCGCATTATTCGCGTTATAGATCGGGCTGTAGAACTGTTCGAGGGTGATAAAGACGAGGCCCAGAA
ATGGTTGAATGAGCCAAACAGAGCACTGAGCTGGAAAGTGCCAGCGGAACTGATGGCCTCCGAAACCGGCGCTTACGAGG
TCATGAAATTGATTACACGCCTGGAGCATGGGGCATACTCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|