Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Hha-TomB/- |
Location | 894027..894652 | Replicon | chromosome |
Accession | NZ_CP017638 | ||
Organism | Dickeya dianthicola RNS04.9 |
Toxin (Protein)
Gene name | Hha | Uniprot ID | E0SD87 |
Locus tag | DDI_RS04365 | Protein ID | WP_009114000.1 |
Coordinates | 894027..894230 (-) | Length | 68 a.a. |
Antitoxin (Protein)
Gene name | TomB | Uniprot ID | A0A3A4CQB3 |
Locus tag | DDI_RS04370 | Protein ID | WP_024104994.1 |
Coordinates | 894284..894652 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DDI_RS04335 | 889476..889814 | + | 339 | WP_024104989.1 | P-II family nitrogen regulator | - |
DDI_RS04340 | 889857..891149 | + | 1293 | WP_024104990.1 | ammonium transporter AmtB | - |
DDI_RS04345 | 891283..892146 | - | 864 | WP_024104991.1 | acyl-CoA thioesterase II | - |
DDI_RS04350 | 892418..892975 | + | 558 | WP_024104992.1 | YbaY family lipoprotein | - |
DDI_RS04355 | 893004..893333 | - | 330 | WP_024104993.1 | MGMT family protein | - |
DDI_RS04365 | 894027..894230 | - | 204 | WP_009114000.1 | hemolysin expression modulator Hha | Toxin |
DDI_RS04370 | 894284..894652 | - | 369 | WP_024104994.1 | Hha toxicity modulator TomB | Antitoxin |
DDI_RS04375 | 895161..895304 | - | 144 | WP_013316871.1 | type B 50S ribosomal protein L36 | - |
DDI_RS04380 | 895320..895571 | - | 252 | WP_024104995.1 | type B 50S ribosomal protein L31 | - |
DDI_RS04385 | 895742..898891 | - | 3150 | WP_024104996.1 | multidrug efflux RND transporter permease subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 68 a.a. Molecular weight: 8133.51 Da Isoelectric Point: 8.8500
>T67872 WP_009114000.1 NZ_CP017638:c894230-894027 [Dickeya dianthicola RNS04.9]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFYSAADHRLAELTMNKLYDKVPTAVWKYVR
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFYSAADHRLAELTMNKLYDKVPTAVWKYVR
Download Length: 204 bp
>T67872 NZ_CP017638:c894230-894027 [Dickeya dianthicola RNS04.9]
ATGAAAAAAATCGACTATTTAATGCGTTTGCGTAAATGCACAACCATCGACACGCTTGAGCGTGTTATAGAAAAAAACAA
GTACGAGCTTTCCAACGATGAGCTTGAAATGTTCTATTCAGCTGCAGACCACCGCCTGGCAGAGCTGACGATGAATAAGC
TTTACGACAAAGTACCGACTGCTGTGTGGAAATACGTTCGTTAA
ATGAAAAAAATCGACTATTTAATGCGTTTGCGTAAATGCACAACCATCGACACGCTTGAGCGTGTTATAGAAAAAAACAA
GTACGAGCTTTCCAACGATGAGCTTGAAATGTTCTATTCAGCTGCAGACCACCGCCTGGCAGAGCTGACGATGAATAAGC
TTTACGACAAAGTACCGACTGCTGTGTGGAAATACGTTCGTTAA
Antitoxin
Download Length: 123 a.a. Molecular weight: 14242.11 Da Isoelectric Point: 5.1811
>AT67872 WP_024104994.1 NZ_CP017638:c894652-894284 [Dickeya dianthicola RNS04.9]
MDEYTPQHYDIAQLRFLCENLHDESIATLGDSSRSWVNDPTSAVNLQLNELIEHIAAFVVTYKIKYPHEAALCERVEKYL
DDTYILFSNYGINDAELQKWRKSKSQLFRMFSEKSICTVVKT
MDEYTPQHYDIAQLRFLCENLHDESIATLGDSSRSWVNDPTSAVNLQLNELIEHIAAFVVTYKIKYPHEAALCERVEKYL
DDTYILFSNYGINDAELQKWRKSKSQLFRMFSEKSICTVVKT
Download Length: 369 bp
>AT67872 NZ_CP017638:c894652-894284 [Dickeya dianthicola RNS04.9]
ATGGATGAGTACACACCTCAACATTATGATATTGCCCAACTCAGATTCTTGTGTGAAAATCTGCACGACGAAAGTATCGC
GACATTAGGTGATAGCAGTCGTAGCTGGGTGAATGACCCGACTTCTGCGGTCAACCTTCAACTAAACGAACTTATCGAGC
ATATTGCGGCATTTGTTGTTACCTACAAAATAAAATACCCGCATGAAGCTGCGTTATGTGAACGGGTTGAGAAATATCTG
GACGACACTTATATTCTTTTCAGTAACTACGGTATAAATGACGCCGAGTTGCAGAAATGGCGAAAATCCAAGTCGCAATT
ATTCAGAATGTTCTCAGAAAAGAGCATCTGTACGGTAGTAAAAACTTAA
ATGGATGAGTACACACCTCAACATTATGATATTGCCCAACTCAGATTCTTGTGTGAAAATCTGCACGACGAAAGTATCGC
GACATTAGGTGATAGCAGTCGTAGCTGGGTGAATGACCCGACTTCTGCGGTCAACCTTCAACTAAACGAACTTATCGAGC
ATATTGCGGCATTTGTTGTTACCTACAAAATAAAATACCCGCATGAAGCTGCGTTATGTGAACGGGTTGAGAAATATCTG
GACGACACTTATATTCTTTTCAGTAACTACGGTATAAATGACGCCGAGTTGCAGAAATGGCGAAAATCCAAGTCGCAATT
ATTCAGAATGTTCTCAGAAAAGAGCATCTGTACGGTAGTAAAAACTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1X3RNQ0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3A4CQB3 |