Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 2032454..2034141 Replicon chromosome
Accession NZ_CP017635
Organism Vibrio vulnificus Env1

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag BJD94_RS10320 Protein ID WP_102983139.1
Coordinates 2032454..2033677 (-) Length 408 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag BJD94_RS10325 Protein ID WP_102983138.1
Coordinates 2033674..2034141 (-) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD94_RS10305 2028690..2030564 + 1875 WP_038940606.1 RNA polymerase sigma factor RpoD -
BJD94_RS10315 2030952..2032193 + 1242 WP_101958315.1 tyrosine-type recombinase/integrase -
BJD94_RS10320 2032454..2033677 - 1224 WP_102983139.1 RelA/SpoT domain-containing protein Toxin
BJD94_RS10325 2033674..2034141 - 468 WP_102983138.1 DUF4065 domain-containing protein Antitoxin
BJD94_RS10330 2034395..2035066 - 672 WP_029847932.1 hypothetical protein -
BJD94_RS10335 2035211..2036248 + 1038 WP_102983137.1 helix-turn-helix domain-containing protein -
BJD94_RS10340 2036415..2037053 + 639 WP_102983136.1 inovirus Gp2 family protein -
BJD94_RS10345 2037094..2037540 - 447 WP_102983135.1 hypothetical protein -
BJD94_RS10350 2037651..2038640 - 990 WP_102983134.1 Flp pilus assembly complex ATPase component TadA -
BJD94_RS10355 2038718..2038906 + 189 WP_102983133.1 AlpA family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2030952..2048868 17916


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(111-228)

Antitoxin

Antitoxin SocA-like, Panacea domain

(32-123)


Sequences

Toxin        


Download         Length: 408 a.a.        Molecular weight: 45963.69 Da        Isoelectric Point: 5.2521

>T67864 WP_102983139.1 NZ_CP017635:c2033677-2032454 [Vibrio vulnificus Env1]
VSDKENSVVSFYIDDTPTAEQASKTFQDDYELDFQDFIERTVNESAAEDFSYSNNGVKKAGRRLRKREGDLKSATATIQQ
FRAAHEKPLNTIAYLVGRCCRELGIDVKPVTRLKRLETIVDKLQRKSLDGETANATCVTNMNDIGGCRAIFPDLISLEKV
QSQLQLTVEKVGRVRIKDIDDYITSPKPNDCGYRSLHVIYRYDHASGKSFNIEAQLRTRLQHLWATTVEIVDILEGTKIK
THSHSSNEDKSSLQIQWEELLSIMSQYIADAEGAKELSDIDKANFSKRLIVLDREINALNRLSSFKILSEKVNSCCDNSI
EHVLLVINETSRELIFSEEFENYSQAISVYNAAEKVTRSYSRSTSRLNTLLISTKNMGQLSEAYPNYLGDCASFITLLED
AMLSGES

Download         Length: 1224 bp

>T67864 NZ_CP017635:c2033677-2032454 [Vibrio vulnificus Env1]
GTGAGTGACAAAGAAAATAGTGTTGTCAGTTTTTACATTGACGACACTCCTACCGCAGAACAAGCTTCAAAAACCTTCCA
AGACGACTACGAGCTGGACTTTCAAGATTTTATAGAAAGAACGGTAAATGAAAGTGCTGCTGAAGACTTCTCGTACTCAA
ATAATGGAGTAAAGAAAGCTGGAAGACGGCTGCGCAAGAGAGAGGGCGACCTCAAGTCAGCTACTGCTACAATCCAACAG
TTTCGAGCCGCACACGAAAAGCCATTAAACACTATCGCATATCTTGTTGGTCGCTGTTGCCGGGAACTGGGTATAGATGT
AAAACCAGTTACACGGTTAAAGCGTTTAGAAACAATCGTAGATAAGTTGCAGCGTAAATCTCTTGATGGTGAAACGGCAA
ATGCTACTTGTGTGACCAATATGAATGATATTGGCGGTTGCAGGGCGATTTTCCCGGATTTAATTTCCTTGGAGAAGGTG
CAATCTCAACTGCAACTTACCGTTGAAAAGGTAGGTCGAGTTAGAATCAAAGATATTGACGATTATATTACTAGCCCTAA
GCCTAATGATTGTGGTTACCGAAGCTTGCATGTAATTTATCGCTATGACCATGCTAGCGGTAAAAGTTTTAACATTGAGG
CTCAGCTACGTACTCGACTTCAACATCTTTGGGCAACTACTGTGGAAATTGTCGACATCCTGGAAGGCACCAAGATTAAG
ACTCACTCTCACAGTTCAAATGAAGATAAGAGTAGTTTACAGATTCAATGGGAAGAATTGCTTTCGATCATGAGCCAGTA
CATTGCTGATGCTGAAGGAGCTAAAGAGCTAAGTGATATCGATAAAGCCAATTTTTCAAAGCGCTTGATCGTCTTGGACC
GCGAAATCAATGCGCTGAATCGATTGAGTAGTTTTAAAATTTTATCTGAAAAGGTGAATTCTTGCTGTGATAACTCTATT
GAGCACGTATTGCTAGTTATTAACGAAACCTCACGAGAATTGATCTTTAGTGAAGAGTTTGAAAATTACAGTCAGGCAAT
TTCAGTTTACAACGCGGCTGAGAAAGTCACTCGTAGCTACTCAAGATCAACCTCGAGACTCAATACCCTTCTCATCTCCA
CAAAAAATATGGGGCAACTTTCGGAAGCCTACCCTAACTATCTAGGCGATTGTGCCTCATTCATCACTCTGCTTGAAGAC
GCAATGCTTTCTGGTGAAAGCTAA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17531.00 Da        Isoelectric Point: 7.9061

>AT67864 WP_102983138.1 NZ_CP017635:c2034141-2033674 [Vibrio vulnificus Env1]
MKAYHTYSAVDVAWSLLKHAKEQGKCFSNLQLQKLTYVCHGLSLAHFQRPLVVDDVFAWKFGPVVPSVYFRFKSYGSSVI
TEQCDIALDQESESIVKDVVSKLGHLTGPQLVDLTHREGSPWHQVWDGTHQKVIPDHLIQAHYTQIKQSGRTASL

Download         Length: 468 bp

>AT67864 NZ_CP017635:c2034141-2033674 [Vibrio vulnificus Env1]
ATGAAAGCATATCACACATACAGTGCTGTAGACGTTGCATGGAGCTTGCTCAAGCATGCGAAAGAGCAAGGTAAATGCTT
CTCCAATTTGCAGCTACAAAAACTTACCTATGTTTGTCATGGTTTATCATTGGCGCATTTCCAACGTCCTCTCGTCGTAG
ATGATGTATTTGCTTGGAAGTTTGGTCCAGTGGTGCCATCTGTTTACTTCCGCTTTAAATCTTACGGTAGTAGTGTGATC
ACTGAACAATGTGATATAGCACTAGACCAAGAAAGTGAGTCTATTGTCAAAGATGTTGTATCTAAACTGGGCCATTTGAC
GGGGCCTCAACTTGTAGATTTAACTCACCGAGAGGGAAGTCCATGGCATCAGGTATGGGATGGCACACACCAAAAAGTGA
TTCCGGATCATTTGATTCAAGCCCATTACACTCAAATCAAACAATCCGGACGAACAGCTAGCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References