Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemK-mazE/MazF(toxin)
Location 2834143..2834768 Replicon chromosome
Accession NZ_CP017634
Organism Candidatus Formimonas warabiya strain DCMF

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag DCMF_RS13125 Protein ID WP_148134828.1
Coordinates 2834143..2834493 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag DCMF_RS13130 Protein ID WP_214659321.1
Coordinates 2834490..2834768 (-) Length 93 a.a.

Genomic Context

DCMF_RS13095DCMF_RS13100DCMF_RS13105DCMF_RS13110DCMF_RS13115DCMF_RS13120DCMF_RS13125DCMF_RS13130DCMF_RS13135DCMF_RS13140DCMF_RS13145DCMF_RS13150DCMF_RS30095
Location: 2829436..2829912 (477 bp)
Type: Others
Protein ID: WP_148134824.1
Location: 2829909..2830622 (714 bp)
Type: Others
Protein ID: WP_148134825.1
Location: 2830603..2831079 (477 bp)
Type: Others
Protein ID: WP_236860330.1
Location: 2831156..2831713 (558 bp)
Type: Others
Protein ID: WP_148137897.1
Location: 2831994..2833103 (1110 bp)
Type: Others
Protein ID: WP_148137898.1
Location: 2833370..2834083 (714 bp)
Type: Others
Protein ID: WP_148134827.1
Location: 2834143..2834493 (351 bp)
Type: Toxin
Protein ID: WP_148134828.1
Location: 2834490..2834768 (279 bp)
Type: Antitoxin
Protein ID: WP_214659321.1
Location: 2834850..2836016 (1167 bp)
Type: Others
Protein ID: WP_148134830.1
Location: 2836013..2837569 (1557 bp)
Type: Others
Protein ID: WP_148134831.1
Location: 2837517..2837951 (435 bp)
Type: Others
Protein ID: WP_148134832.1
Location: 2838181..2838504 (324 bp)
Type: Others
Protein ID: WP_148134833.1
Location: 2838528..2838653 (126 bp)
Type: Others
Protein ID: WP_257790960.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
DCMF_RS13095 (DCMF_13100)2829436..2829912-477WP_148134824.1ribosomal protein S18-alanine N-acetyltransferase-
DCMF_RS13100 (DCMF_13105)2829909..2830622-714WP_148134825.1tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB-
DCMF_RS13105 (DCMF_13110)2830603..2831079-477WP_236860330.1tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE-
DCMF_RS13110 (DCMF_13115)2831156..2831713-558WP_148137897.1uracil-DNA glycosylase-
DCMF_RS13115 (DCMF_13120)2831994..2833103-1110WP_148137898.1amidohydrolase-
DCMF_RS13120 (DCMF_13125)2833370..2834083-714WP_148134827.1gamma-glutamyl-gamma-aminobutyrate hydrolase family protein-
DCMF_RS13125 (DCMF_13130)2834143..2834493-351WP_148134828.1type II toxin-antitoxin system PemK/MazF family toxinToxin
DCMF_RS13130 (DCMF_13135)2834490..2834768-279WP_214659321.1ribbon-helix-helix protein, CopG familyAntitoxin
DCMF_RS13135 (DCMF_13140)2834850..2836016-1167WP_148134830.1alanine racemase-
DCMF_RS13140 (DCMF_13145)2836013..2837569-1557WP_148134831.1NAD(P)H-hydrate dehydratase-
DCMF_RS13145 (DCMF_13150)2837517..2837951-435WP_148134832.1holo-ACP synthase-
DCMF_RS13150 (DCMF_13155)2838181..2838504-324WP_148134833.1hypothetical protein-
DCMF_RS300952838528..2838653-126WP_257790960.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12816.82 Da        Isoelectric Point: 6.4740

>T67856 WP_148134828.1 NZ_CP017634:c2834493-2834143 [Candidatus Formimonas warabiya]
MIVRRGEVFFAELNPVQGSEQGGTRPVLVVQNDVGNQYSPTTIVVAITSQINKAKLPTHVELPKEKTGLDKDSVILAEQV
RTIDKSRLQHKVAMLGEEIMNRVDRALEISLGLVEI

Download         Length: 351 bp

>T67856 NZ_CP017634:c2834493-2834143 [Candidatus Formimonas warabiya]
ATGATTGTACGGCGCGGGGAAGTGTTTTTTGCCGAGCTAAATCCTGTCCAAGGTTCAGAGCAGGGAGGCACCAGGCCTGT
TTTGGTAGTACAAAATGATGTCGGCAACCAATACAGCCCAACTACTATTGTTGTTGCCATTACCTCTCAGATTAACAAAG
CAAAATTGCCTACGCATGTAGAACTGCCTAAAGAAAAAACAGGGCTTGATAAAGATTCGGTAATTTTAGCCGAACAGGTA
CGCACCATTGACAAAAGCCGCCTTCAGCATAAGGTTGCCATGCTGGGGGAAGAGATTATGAATCGGGTAGACCGGGCATT
GGAGATCAGTTTAGGATTAGTGGAAATATAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 11010.68 Da        Isoelectric Point: 7.2455

>AT67856 WP_214659321.1 NZ_CP017634:c2834768-2834490 [Candidatus Formimonas warabiya]
VPNLKRIMISIPDQLLQEFDGLVNHENKNRSEFIREAMKFYIAERRRRILHEQMKKGYQEMANINLSIARECFSMEHEAF
EDPGEKIAECRK

Download         Length: 279 bp

>AT67856 NZ_CP017634:c2834768-2834490 [Candidatus Formimonas warabiya]
GTGCCGAATTTAAAGCGAATTATGATTAGTATCCCGGATCAGCTGCTGCAAGAGTTTGATGGATTGGTGAATCATGAAAA
TAAGAACAGGAGCGAGTTTATCCGGGAAGCGATGAAGTTTTATATTGCCGAACGTCGCCGGCGCATCCTGCATGAACAGA
TGAAAAAGGGATATCAGGAGATGGCAAATATTAATTTATCTATTGCCCGGGAATGTTTCAGTATGGAACATGAGGCCTTT
GAAGACCCCGGAGAAAAAATAGCGGAGTGTCGCAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References