67855

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1408524..1409076 Replicon chromosome
Accession NZ_CP017634
Organism Candidatus Formimonas warabiya strain DCMF

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DCMF_RS06695 Protein ID WP_148133708.1
Coordinates 1408801..1409076 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DCMF_RS06690 Protein ID WP_214659386.1
Coordinates 1408524..1408808 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCMF_RS06680 (DCMF_06675) 1407853..1408125 - 273 WP_148133705.1 Txe/YoeB family addiction module toxin -
DCMF_RS06685 (DCMF_06680) 1408118..1408360 - 243 WP_148133706.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
DCMF_RS06690 (DCMF_06685) 1408524..1408808 + 285 WP_214659386.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DCMF_RS06695 (DCMF_06690) 1408801..1409076 + 276 WP_148133708.1 type II toxin-antitoxin system YafQ family toxin Toxin
DCMF_RS06700 (DCMF_06695) 1409284..1409712 - 429 WP_148133709.1 HEPN domain-containing protein -
DCMF_RS06705 (DCMF_06700) 1409705..1410025 - 321 WP_148133710.1 nucleotidyltransferase domain-containing protein -
DCMF_RS06710 (DCMF_06710) 1410403..1411614 - 1212 WP_148133711.1 DUF2791 family P-loop domain-containing protein -
DCMF_RS06715 (DCMF_06715) 1411614..1412834 - 1221 WP_236860208.1 DUF2791 family P-loop domain-containing protein -
DCMF_RS06720 (DCMF_06720) 1412838..1413713 - 876 WP_236860209.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-70)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10597.30 Da        Isoelectric Point: 8.4985

>T67855 WP_148133708.1 NZ_CP017634:1408801-1409076 [Candidatus Formimonas warabiya]
MYEIKPTSRFKRDLKIIQRRGYDINLLTAVIQTLAAGEPLAEKHKDHALNGVWTKYRECHVTPDWLLIYKVENDILVLTL
TRTGTHSDLFC

Download         Length: 276 bp

>T67855 NZ_CP017634:1408801-1409076 [Candidatus Formimonas warabiya]
ATGTATGAGATAAAACCAACCAGTCGTTTCAAGCGTGATTTGAAAATCATCCAGCGCAGAGGTTATGATATTAACCTGCT
CACAGCGGTTATCCAAACATTGGCTGCCGGGGAGCCTCTGGCAGAAAAACATAAAGATCATGCTTTGAACGGCGTTTGGA
CAAAGTACAGGGAATGCCACGTCACACCGGATTGGCTGCTCATTTATAAGGTGGAAAATGACATCCTTGTTCTCACTCTT
ACCCGTACAGGAACACACAGTGATTTATTTTGTTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10647.27 Da        Isoelectric Point: 4.6151

>AT67855 WP_214659386.1 NZ_CP017634:1408524-1408808 [Candidatus Formimonas warabiya]
IMANTTNISIRMDVELKKQAEQLFNELGMSMTTAFNIFLRQAVRQQRIPFDIALETPNAETIAAIEEAERISRDPSVKGY
TDASKMMKELLPDV

Download         Length: 285 bp

>AT67855 NZ_CP017634:1408524-1408808 [Candidatus Formimonas warabiya]
ATTATGGCTAATACAACGAATATAAGCATCCGCATGGACGTTGAGCTTAAAAAACAGGCTGAGCAGCTTTTCAACGAGCT
CGGTATGAGCATGACGACGGCCTTTAATATTTTTCTGCGTCAAGCTGTGCGTCAGCAGAGAATTCCCTTCGATATTGCTC
TAGAGACTCCCAACGCCGAGACAATCGCTGCCATCGAGGAAGCTGAACGCATCAGTCGCGATCCTTCGGTCAAAGGCTAT
ACTGACGCAAGTAAAATGATGAAGGAGCTTTTGCCCGATGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References