67801

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 5097608..5098311 Replicon chromosome
Accession NZ_CP017599
Organism Moorea producens PAL-8-15-08-1

Toxin (Protein)


Gene name tad Uniprot ID A0A1D8TUA3
Locus tag BJP34_RS18690 Protein ID WP_070393642.1
Coordinates 5097608..5097976 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID A0A1D8TU80
Locus tag BJP34_RS18695 Protein ID WP_070393643.1
Coordinates 5097988..5098311 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJP34_RS43680 5093355..5093504 + 150 WP_158517299.1 hypothetical protein -
BJP34_RS18675 5094128..5095510 - 1383 WP_070396755.1 chromosomal replication initiator protein DnaA -
BJP34_RS18680 5095700..5096236 + 537 WP_070393641.1 peptide deformylase -
BJP34_RS37170 5096491..5097357 - 867 Protein_4187 IS5 family transposase -
BJP34_RS43685 5097426..5097566 + 141 WP_158517300.1 hypothetical protein -
BJP34_RS18690 5097608..5097976 + 369 WP_070393642.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BJP34_RS18695 5097988..5098311 + 324 WP_070393643.1 helix-turn-helix domain-containing protein Antitoxin
BJP34_RS18700 5098423..5100180 - 1758 WP_070393644.1 arginine--tRNA ligase -
BJP34_RS43690 5100284..5100472 + 189 WP_158517301.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-89)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13719.73 Da        Isoelectric Point: 8.7628

>T67801 WP_070393642.1 NZ_CP017599:5097608-5097976 [Moorea producens PAL-8-15-08-1]
MDVSLKPVEWVGSSLEDLKKFPSEVQQVIGYALYLAQCGDKHPGAKPLKGLKGAGVLEVIDNFDGDTYRGVYTVKLQGVV
YVLHTFQKKSKQGIATPKQELELIEARLKRAREHYSQHYTNE

Download         Length: 369 bp

>T67801 NZ_CP017599:5097608-5097976 [Moorea producens PAL-8-15-08-1]
ATGGATGTGTCCTTAAAACCTGTAGAGTGGGTTGGCAGTTCCTTGGAAGATTTGAAAAAATTTCCCTCAGAAGTTCAGCA
AGTGATCGGTTATGCCTTGTACTTAGCTCAATGTGGAGACAAACATCCCGGTGCTAAACCCCTCAAAGGATTGAAAGGTG
CTGGTGTACTCGAAGTTATTGACAACTTTGATGGAGACACTTATCGGGGTGTATACACCGTAAAACTCCAAGGTGTAGTG
TATGTTCTGCATACATTTCAAAAGAAATCAAAGCAAGGTATCGCCACACCCAAGCAAGAGCTGGAATTAATTGAAGCCAG
GTTAAAAAGAGCCAGAGAACATTACTCACAACATTACACTAACGAGTAG

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11390.30 Da        Isoelectric Point: 9.9512

>AT67801 WP_070393643.1 NZ_CP017599:5097988-5098311 [Moorea producens PAL-8-15-08-1]
MVKEIEVQASSGNVFADLGLENSDELIVKAELARKISSIIANQGMTQAAAAKVLGVDQPKVSALINGKLAGFSIVRLFRF
LNAFGQDVEIVVKTKPLSHPVARTLVS

Download         Length: 324 bp

>AT67801 NZ_CP017599:5097988-5098311 [Moorea producens PAL-8-15-08-1]
ATGGTAAAAGAAATTGAAGTACAAGCTAGTAGTGGTAATGTGTTTGCCGATTTAGGTTTAGAAAACTCTGATGAATTAAT
CGTTAAAGCAGAACTGGCTCGTAAGATTAGTAGTATTATTGCCAACCAGGGTATGACACAAGCGGCGGCGGCCAAGGTTT
TAGGAGTAGATCAGCCTAAAGTGTCCGCACTTATCAATGGTAAGTTGGCTGGTTTTTCAATTGTGCGGCTGTTTCGCTTC
TTAAACGCTTTCGGTCAAGATGTGGAAATTGTGGTCAAAACCAAACCATTATCTCACCCTGTGGCTCGAACACTAGTGTC
GTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D8TUA3

Antitoxin

Source ID Structure
AlphaFold DB A0A1D8TU80

References