Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 1494483..1495042 Replicon chromosome
Accession NZ_CP017599
Organism Moorea producens PAL-8-15-08-1

Toxin (Protein)


Gene name vapC Uniprot ID A0A1D8TMX8
Locus tag BJP34_RS05715 Protein ID WP_070391508.1
Coordinates 1494704..1495042 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1D8TMY4
Locus tag BJP34_RS05710 Protein ID WP_070391507.1
Coordinates 1494483..1494707 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJP34_RS05700 1490191..1492755 - 2565 WP_070391505.1 filamentous hemagglutinin N-terminal domain-containing protein -
BJP34_RS42520 1492899..1493042 - 144 WP_158517034.1 hypothetical protein -
BJP34_RS05705 1493268..1494170 + 903 WP_070391506.1 alpha/beta hydrolase -
BJP34_RS05710 1494483..1494707 + 225 WP_070391507.1 DUF433 domain-containing protein Antitoxin
BJP34_RS05715 1494704..1495042 + 339 WP_070391508.1 DUF5615 family PIN-like protein Toxin
BJP34_RS05720 1495661..1497940 + 2280 WP_070391509.1 AAA family ATPase -
BJP34_RS42525 1497915..1498070 + 156 WP_158517035.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12359.07 Da        Isoelectric Point: 4.0158

>T67799 WP_070391508.1 NZ_CP017599:1494704-1495042 [Moorea producens PAL-8-15-08-1]
MTIWVDANLSPGIATWINNTFGVTALALRDIGLRDAEDPEIFEAAKAQSVIFMTKDSDFVDLVDRLGSPPQIIWLTCGNT
SNDRLREILTVTLPEALELLRSGETLVEIRGD

Download         Length: 339 bp

>T67799 NZ_CP017599:1494704-1495042 [Moorea producens PAL-8-15-08-1]
ATGACAATTTGGGTAGACGCAAATTTGTCGCCTGGGATTGCAACTTGGATTAACAATACTTTTGGAGTGACAGCATTAGC
TTTACGGGATATTGGTTTGAGAGATGCTGAAGATCCTGAGATTTTTGAGGCAGCAAAGGCTCAAAGCGTTATCTTCATGA
CTAAAGACAGTGATTTTGTCGATCTAGTCGATCGCCTTGGCTCACCACCTCAAATTATCTGGTTGACCTGTGGTAACACC
TCAAATGATCGGTTGCGAGAAATTTTGACTGTTACTTTACCAGAAGCACTAGAGCTTCTACGGTCTGGTGAAACATTAGT
TGAAATTAGGGGAGACTAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8156.60 Da        Isoelectric Point: 7.8335

>AT67799 WP_070391507.1 NZ_CP017599:1494483-1494707 [Moorea producens PAL-8-15-08-1]
MSDLLKRITINPRQCGGRPCIRGMRIRVSDVLDLFAAGLSAEQILAEMPDLEANDLQAALLYASRKLNHPVLVP

Download         Length: 225 bp

>AT67799 NZ_CP017599:1494483-1494707 [Moorea producens PAL-8-15-08-1]
ATGTCAGATTTGCTTAAAAGAATTACCATTAATCCGAGACAGTGCGGTGGTCGCCCTTGTATTCGAGGTATGAGAATTAG
AGTATCCGATGTACTGGATTTGTTTGCGGCTGGACTGAGTGCTGAGCAAATCTTAGCAGAAATGCCTGATTTAGAAGCAA
ATGATTTGCAGGCAGCACTTCTATATGCCTCACGTAAGCTTAATCATCCGGTGCTGGTGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D8TMX8

Antitoxin

Source ID Structure
AlphaFold DB A0A1D8TMY4

References