Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 43091..43671 Replicon plasmid pDSJ07
Accession NZ_CP017588
Organism Pantoea stewartii subsp. stewartii DC283

Toxin (Protein)


Gene name parE Uniprot ID H3RG02
Locus tag DSJ_RS23950 Protein ID WP_006120406.1
Coordinates 43091..43396 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7U5G6Q4
Locus tag DSJ_RS23955 Protein ID WP_044242376.1
Coordinates 43384..43671 (-) Length 96 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSJ_RS23925 38695..39678 + 984 WP_006120403.1 recombinase family protein -
DSJ_RS23930 39701..40036 - 336 WP_044242374.1 hypothetical protein -
DSJ_RS23935 40033..40740 - 708 WP_044242375.1 ParA family protein -
DSJ_RS23945 41943..42809 - 867 WP_006120404.1 incFII family plasmid replication initiator RepA -
DSJ_RS23950 43091..43396 - 306 WP_006120406.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
DSJ_RS23955 43384..43671 - 288 WP_044242376.1 ribbon-helix-helix protein, CopG family Antitoxin
DSJ_RS23960 43915..44214 + 300 WP_167387070.1 PAS domain-containing protein -
DSJ_RS23965 44247..46155 - 1909 Protein_47 Tn3 family transposase -
DSJ_RS23970 46229..46858 + 630 WP_044241253.1 IS66 family insertion sequence hypothetical protein -
DSJ_RS23975 46855..47202 + 348 WP_006117592.1 IS66 family insertion sequence element accessory protein TnpB -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..65483 65483


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 102 a.a.        Molecular weight: 15030.03 Da        Isoelectric Point: 5.5500

>T67432 WP_006120406.1 NZ_CP017588:c43396-43091 [Pantoea stewartii subsp. stewartii DC283]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFF

Download         Length: 306 bp

>T67432 NZ_CP017588:c43396-43091 [Pantoea stewartii subsp. stewartii DC283]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 14146.97 Da        Isoelectric Point: 5.5500

>AT67432 WP_044242376.1 NZ_CP017588:c43671-43384 [Pantoea stewartii subsp. stewartii DC283]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFF

Download         Length: 288 bp

>AT67432 NZ_CP017588:c43671-43384 [Pantoea stewartii subsp. stewartii DC283]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB H3RG02


Antitoxin

Source ID Structure
AlphaFold DB A0A7U5G6Q4

References