Detailed information of TA system TA067431

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 7612..8141
• Replicon: plasmid pDSJ07
• Accession: NZ_CP017588
• Organism: Pantoea stewartii subsp. stewartii DC283

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: -
• Locus tag: DSJ_RS23750
• Protein ID: WP_044243550.1
• Coordinates: 7612..7896 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: A0A7U5G6T6
• Locus tag: DSJ_RS23755
• Protein ID: WP_044243551.1
• Coordinates: 7896..8141 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DSJ_RS23725	3232..3438	-	207	WP_080577525.1	Hin recombinase	-
DSJ_RS23730	3610..4803	-	1194	WP_006122348.1	IS4 family transposase	-
DSJ_RS23735	5036..5401	+	366	WP_141119424.1	topoisomerase C-terminal repeat-containing protein	-
DSJ_RS23740	5398..5787	+	390	WP_006122350.1	H-NS histone family protein	-
DSJ_RS23745	6430..7449	+	1020	Protein_6	MFS transporter	-
DSJ_RS23750	7612..7896	-	285	WP_044243550.1	CcdB family protein	Toxin
DSJ_RS23755	7896..8141	-	246	WP_044243551.1	type II toxin-antitoxin system CcdA family antitoxin	Antitoxin
DSJ_RS23760	8200..8412	-	213	WP_044243552.1	type II toxin-antitoxin system MqsA family antitoxin	-
DSJ_RS23765	8405..8659	-	255	WP_044243555.1	hypothetical protein	-
DSJ_RS23770	8656..9198	-	543	WP_044243569.1	hypothetical protein	-
DSJ_RS23775	9666..10853	-	1188	WP_006118957.1	IS4 family transposase	-
DSJ_RS23780	10969..11511	+	543	WP_044243557.1	hypothetical protein	-
DSJ_RS23785	11578..11790	+	213	WP_006122356.1	hypothetical protein	-
DSJ_RS23790	11780..11998	+	219	WP_044243560.1	hypothetical protein	-
DSJ_RS23795	12096..12425	+	330	WP_044243562.1	hypothetical protein	-
DSJ_RS23800	12477..12671	+	195	WP_006122357.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..65483	65483

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HicA mRNA interferase family (4-59)

Antitoxin

• HicB-like antitoxin of toxin-antitoxin system (3-129)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 13999.79 Da
• Isoelectric Point: 5.5500

>T67431 WP_044243550.1 NZ_CP017588:c7896-7612 [Pantoea stewartii subsp. stewartii DC283]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFF

Nucleotide

• Length: 285 bp

>T67431 NZ_CP017588:c7896-7612 [Pantoea stewartii subsp. stewartii DC283]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 12086.50 Da
• Isoelectric Point: 5.5500

>AT67431 WP_044243551.1 NZ_CP017588:c8141-7896 [Pantoea stewartii subsp. stewartii DC283]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FF

Nucleotide

• Length: 246 bp

>AT67431 NZ_CP017588:c8141-7896 [Pantoea stewartii subsp. stewartii DC283]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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Structures

Antitoxin

• AlphaFold DB: A0A7U5G6T6