Detailed information of TA system TA066907

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 1732015..1732764
• Replicon: chromosome
• Accession: NZ_CP017483
• Organism: Stenotrophomonas sp. LM091

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: BIZ42_RS07595
• Protein ID: WP_083298780.1
• Coordinates: 1732015..1732404 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: A0A1D8Y932
• Locus tag: BIZ42_RS07600
• Protein ID: WP_070426052.1
• Coordinates: 1732495..1732764 (-)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BIZ42_RS07590	1728934..1731999	+	3066	WP_070426050.1	efflux RND transporter permease subunit	-
BIZ42_RS07595	1732015..1732404	-	390	WP_083298780.1	GNAT family N-acetyltransferase	Toxin
BIZ42_RS07600	1732495..1732764	-	270	WP_070426052.1	DUF1778 domain-containing protein	Antitoxin
BIZ42_RS07605	1732943..1734046	-	1104	WP_070427476.1	3-deoxy-7-phosphoheptulonate synthase AroG	-
BIZ42_RS07610	1734286..1734633	-	348	WP_019183559.1	hypothetical protein	-
BIZ42_RS07615	1734648..1735388	-	741	WP_070426053.1	DNA alkylation repair protein	-
BIZ42_RS07620	1735385..1735879	-	495	WP_070426054.1	MarR family transcriptional regulator	-
BIZ42_RS07625	1736010..1736294	+	285	WP_070426055.1	hypothetical protein	-
BIZ42_RS07630	1736411..1737571	+	1161	WP_070426056.1	serine hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (15-115)

Antitoxin

• Vibrio phage ICP1, Orf50 (8-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 13872.19 Da
• Isoelectric Point: 8.9953

>T66907 WP_083298780.1 NZ_CP017483:c1732404-1732015 [Stenotrophomonas sp. LM091]
MERAHQNQASGASRCFVVCDAQHNVVGYYALAAGGVSHQLVPGRLRRNMPHPIPVIVLCRLAVHADWVGQGVGAGLLKDA
VQRTMQVCGHIGARALLCHAFDDTAKAFYLKHGFIASPMDGRTMMLPVA

Nucleotide

• Length: 390 bp

>T66907 NZ_CP017483:c1732404-1732015 [Stenotrophomonas sp. LM091]
ATGGAGCGTGCCCACCAGAACCAGGCATCGGGGGCATCGCGGTGTTTTGTTGTGTGTGATGCGCAACACAATGTGGTGGG
CTATTACGCGCTCGCTGCCGGCGGCGTTTCGCACCAGCTGGTTCCCGGTCGCCTTCGCCGGAACATGCCGCACCCCATTC
CGGTCATCGTGCTGTGCAGGTTGGCCGTCCATGCCGACTGGGTCGGCCAGGGCGTCGGCGCGGGACTGCTGAAAGACGCT
GTGCAACGCACGATGCAGGTCTGCGGGCACATCGGCGCGCGCGCCTTGTTGTGTCATGCGTTCGACGACACTGCCAAAGC
GTTCTATCTCAAGCATGGCTTCATCGCGTCGCCGATGGATGGCAGGACGATGATGTTGCCTGTTGCATAG

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9874.30 Da
• Isoelectric Point: 6.2918

>AT66907 WP_070426052.1 NZ_CP017483:c1732764-1732495 [Stenotrophomonas sp. LM091]
VALASKVINFRAPADKQALIDRAVEVTGVSRTEFILDAACEKAREVLADQTQFSLDPQQLRRFNALLDAPLENNAAIRKL
LSTPAPWER

Nucleotide

• Length: 270 bp

>AT66907 NZ_CP017483:c1732764-1732495 [Stenotrophomonas sp. LM091]
GTGGCCCTCGCCAGCAAAGTCATCAACTTCCGGGCGCCCGCCGACAAGCAGGCGCTGATCGACCGCGCCGTTGAGGTTAC
CGGGGTGAGCCGAACCGAGTTCATTCTGGATGCTGCCTGTGAGAAGGCGCGGGAGGTACTCGCGGACCAGACACAGTTCT
CCCTGGATCCTCAGCAGCTGCGACGCTTTAATGCGTTGCTGGATGCACCGCTGGAAAACAACGCGGCCATCAGGAAACTG
TTGAGCACGCCTGCACCCTGGGAGCGCTGA

Structures

Antitoxin

• AlphaFold DB: A0A1D8Y932