Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4604887..4605547 Replicon chromosome
Accession NZ_CP017482
Organism Pectobacterium polaris strain NIBIO1392

Toxin (Protein)


Gene name cptA Uniprot ID A0A093S6F1
Locus tag BJK05_RS20870 Protein ID WP_039487287.1
Coordinates 4605134..4605547 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A093SCR9
Locus tag BJK05_RS20865 Protein ID WP_039487284.1
Coordinates 4604887..4605153 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJK05_RS20845 4600891..4601895 - 1005 WP_095701612.1 substrate-binding domain-containing protein -
BJK05_RS20850 4601950..4602558 - 609 WP_095701613.1 HD domain-containing protein -
BJK05_RS20855 4602948..4603595 + 648 WP_039487281.1 hemolysin III family protein -
BJK05_RS20860 4603650..4604651 - 1002 WP_095701614.1 tRNA-modifying protein YgfZ -
BJK05_RS20865 4604887..4605153 + 267 WP_039487284.1 FAD assembly factor SdhE Antitoxin
BJK05_RS20870 4605134..4605547 + 414 WP_039487287.1 protein YgfX Toxin
BJK05_RS20875 4605616..4606551 + 936 WP_095701615.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
BJK05_RS20880 4606617..4606940 - 324 WP_095701616.1 hypothetical protein -
BJK05_RS20885 4606969..4607487 - 519 WP_095701617.1 flavodoxin FldB -
BJK05_RS20890 4607827..4608213 - 387 WP_095701618.1 thioesterase family protein -
BJK05_RS20895 4608438..4609760 - 1323 WP_095701619.1 MHS family MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16297.28 Da        Isoelectric Point: 10.6913

>T66906 WP_039487287.1 NZ_CP017482:4605134-4605547 [Pectobacterium polaris]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQKNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLRAVNGKDKQQLWLASDSMGDEEWRHLRQLLLQQKHWAR

Download         Length: 414 bp

>T66906 NZ_CP017482:4605134-4605547 [Pectobacterium polaris]
GTGGCCCAGTGGCAATGTGACCTTCGTGTTTCCTGGCGCATGCAACTGCTGTCATTGGTTGTGCATGGCCTATTAGTATT
GCTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCATGGCTATGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAAAAGAATATCAAATCCCGACAGGGGGAAATCGTTCTGCTTAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAGATCGTTAAACGACCGTGGCTGCTGAAGAATGGCGTATTGCTGTCATTGCGAGCGGTTAACGGTAAAGACAA
GCAACAGCTGTGGCTGGCATCGGACAGCATGGGTGATGAAGAGTGGCGTCACTTGCGTCAGCTTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10489.90 Da        Isoelectric Point: 5.1392

>AT66906 WP_039487284.1 NZ_CP017482:4604887-4605153 [Pectobacterium polaris]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRIISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT66906 NZ_CP017482:4604887-4605153 [Pectobacterium polaris]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGTCGCCGTGGTATGCGCGAACTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTTAATGACACGGATAAGCGCACGTTTGTCCGCTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGGAGGACGGAGAGCTGAAACGCATTATTTCCCTTATTCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A093S6F1

Antitoxin

Source ID Structure
AlphaFold DB A0A093SCR9

References