Detailed information of TA system TA066901

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 4152174..4152705
• Replicon: chromosome
• Accession: NZ_CP017482
• Organism: Pectobacterium polaris strain NIBIO1392

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: BJK05_RS18865
• Protein ID: WP_095701318.1
• Coordinates: 4152418..4152705 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: A0A1V2R9J2
• Locus tag: BJK05_RS18860
• Protein ID: WP_039282788.1
• Coordinates: 4152174..4152428 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BJK05_RS18835	4147416..4148006	-	591	WP_011091952.1	DnaA initiator-associating protein DiaA	-
BJK05_RS18840	4148070..4148426	-	357	WP_039279491.1	YraN family protein	-
BJK05_RS18845	4148423..4150441	-	2019	WP_095701316.1	penicillin-binding protein activator	-
BJK05_RS18850	4150503..4151390	+	888	WP_095701317.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
BJK05_RS18860	4152174..4152428	+	255	WP_039282788.1	plasmid stabilization protein	Antitoxin
BJK05_RS18865	4152418..4152705	+	288	WP_095701318.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BJK05_RS18870	4152882..4153667	+	786	WP_095701319.1	4,5-DOPA dioxygenase extradiol	-
BJK05_RS18875	4153737..4154897	-	1161	WP_095701320.1	glutathionylspermidine synthase family protein	-
BJK05_RS18880	4154909..4155583	-	675	WP_095701321.1	DUF1190 family protein	-
BJK05_RS18885	4155855..4157249	-	1395	WP_095701322.1	outer membrane channel protein TolC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-74)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10935.81 Da
• Isoelectric Point: 10.7694

>T66901 WP_095701318.1 NZ_CP017482:4152418-4152705 [Pectobacterium polaris]
MTYKLKFVPSALKEWKKLGHPVREQFKKKLVERLENPRVPSAQPHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGGGK
REGSQIYSDTKGRSA

Nucleotide

• Length: 288 bp

>T66901 NZ_CP017482:4152418-4152705 [Pectobacterium polaris]
ATGACCTATAAGTTAAAATTTGTGCCTTCTGCGCTGAAGGAATGGAAAAAGTTAGGGCATCCTGTCCGGGAGCAATTCAA
GAAAAAACTGGTTGAGCGCTTGGAAAATCCTCGTGTTCCTTCAGCACAGCCTCACGGCCGTAAAGATCAGTATAAAATTA
AACTGAAGTCCGCTGGCTACAGGCTGGTGTATTTGGTCCAGGATGAGACCATTACTGTGATGGTTATGGGGGGGGGAAAG
CGCGAAGGTAGCCAGATTTATTCTGATACTAAAGGTCGCTCTGCTTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9208.38 Da
• Isoelectric Point: 3.7947

>AT66901 WP_039282788.1 NZ_CP017482:4152174-4152428 [Pectobacterium polaris]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT66901 NZ_CP017482:4152174-4152428 [Pectobacterium polaris]
ATGGCTTTCAACATCCTAACTAACACTGCGGCCAGTATTACTGAGTTGAAACGTGACCCTATGGGGACGGTACGGGCTGC
TGAAGGTGAAACTATCGCTATACTGAACCGGAATGAACCGGCGTTCTACTGTGTGCCTCCTGCCGTATTCGCATATTTAA
TGGAACTGGCCGAAGATGCAGAACTGGGGCGTACCGTTGATGATCGGATGTCAGAGTTAGCTGACGCGGAAGAGATTTCG
CTCGATGACCTATAA

Structures

Antitoxin

• AlphaFold DB: A0A1V2R9J2