Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 2853781..2854421 Replicon chromosome
Accession NZ_CP017482
Organism Pectobacterium polaris strain NIBIO1392

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag BJK05_RS12940 Protein ID WP_095700535.1
Coordinates 2853781..2854197 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag BJK05_RS12945 Protein ID WP_095700536.1
Coordinates 2854194..2854421 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJK05_RS12920 2849423..2850757 + 1335 WP_095700531.1 type I-F CRISPR-associated protein Csy1 -
BJK05_RS12925 2850754..2851686 + 933 WP_095700532.1 type I-F CRISPR-associated protein Csy2 -
BJK05_RS12930 2851700..2852710 + 1011 WP_095700533.1 type I-F CRISPR-associated protein Csy3 -
BJK05_RS12935 2852720..2853274 + 555 WP_095700534.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
BJK05_RS12940 2853781..2854197 - 417 WP_095700535.1 type II toxin-antitoxin system VapC family toxin Toxin
BJK05_RS12945 2854194..2854421 - 228 WP_095700536.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BJK05_RS12950 2855571..2855990 - 420 WP_095700537.1 secondary thiamine-phosphate synthase enzyme YjbQ -
BJK05_RS12955 2856006..2858840 - 2835 WP_095700538.1 excinuclease ABC subunit UvrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-129)

Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15189.74 Da        Isoelectric Point: 9.3444

>T66896 WP_095700535.1 NZ_CP017482:c2854197-2853781 [Pectobacterium polaris]
VSRLFMLDTNICSFIMREHPAAVIEKLQQCTLRRDRIVVSAITYAEMRFGAVGKKASPRHMQLVDAFCRRLDAVLPWDSA
AVDATTKIKIALAAAGTPIGPNDTAIAGHAISAKAILVTNNLREFERVQGLTLEDWVK

Download         Length: 417 bp

>T66896 NZ_CP017482:c2854197-2853781 [Pectobacterium polaris]
GTGAGTCGCTTGTTCATGCTGGATACCAATATCTGTTCCTTCATTATGCGTGAACACCCTGCGGCGGTGATTGAAAAGTT
GCAGCAGTGCACATTGCGGCGTGATCGGATCGTGGTCTCTGCTATCACTTACGCTGAAATGCGTTTCGGGGCGGTTGGAA
AAAAAGCCTCGCCACGCCATATGCAACTAGTTGATGCTTTCTGTCGTCGACTCGATGCGGTGTTACCTTGGGATAGCGCC
GCAGTAGACGCTACTACGAAAATCAAAATTGCGTTAGCCGCCGCTGGCACGCCTATTGGCCCAAATGATACAGCCATCGC
TGGTCATGCCATCAGCGCTAAGGCCATATTGGTTACCAATAATCTGAGAGAGTTTGAGCGAGTACAGGGGCTAACGTTGG
AAGATTGGGTTAAATAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8908.08 Da        Isoelectric Point: 4.5216

>AT66896 WP_095700536.1 NZ_CP017482:c2854421-2854194 [Pectobacterium polaris]
MRIVSVFKNGNNRAIRLPRDMDFEGVNELEIVREGDTIMLRPVKPNWHSFLQEERADADFMTERQDIVEEGRFEL

Download         Length: 228 bp

>AT66896 NZ_CP017482:c2854421-2854194 [Pectobacterium polaris]
ATGCGTATTGTTTCGGTATTTAAAAACGGTAACAACCGTGCCATTCGCTTGCCACGTGATATGGACTTTGAAGGGGTCAA
CGAACTGGAGATCGTGCGTGAGGGGGACACCATCATGCTGCGTCCGGTTAAACCCAATTGGCATTCATTTTTGCAAGAAG
AGCGCGCTGACGCTGACTTTATGACAGAACGTCAGGATATAGTCGAAGAGGGGAGATTCGAACTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References